Doi: 10.1038 nature03197 1. Beddell, C. R., Goodford, P. J., Norrington, F. E., Wilkinson, S. & Wootton, R. Compounds designed to fit a site of known structure in human haemoglobin. Br. J. Pharmacol. 57, 201209 1976 ; . 2. Cohen, S. S. A strategy for the chemotherapy of infectious disease. Science 197, 431432 1977 ; . 3. Itzstein, M. V. et al. Rational design of potent sialidase-based inhibitors of influenza virus replication. Nature 363, 418423 1993 ; . 4. Varney, M. D. et al. Crystal-structure-based design and synthesis of Benz[cd]indole-containing inhibitors of thymidylate synthase. J. Med. Chem. 35, 663676 1992 ; . 5. Kuntz, I. D. Structure-based strategies for drug design and discovery. Science 257, 10781082 1992 ; . 6. Jorgensen, W. L. The many roles of computation in drug discovery. Science 303, 18131818 2004 ; . 7. Stahura, F. L. & Bajorath, J. Virtual screening methods that complement HTS. Comb. Chem. High Throughput Screen 7, 259269 2004 ; . 8. Perutz, M. F. The hemaglobin molecule. Sci. Am. 211, 6476 1964 ; . 9. van Gunsteren, W. F. & Berendsen, H. J. C. Computer simulation of molecular dynamics: methodology, applications, and perspectives in chemistry. Angew. Chem. Int. Ed. Engl. 29, 9921023 1990 ; . 10. Rizzo, R., Wang, D., Tirado-Rives, J. & Jorgensen, W. Validation of a model for the complex of HIV-1 reverse transcriptase with sustiva through computation of resistance profiles. J. Am. Chem. Soc. 122, 1289812900 2000 ; . 11. Rosenfeld, R. J. et al. Automated docking of ligands to an artificial active site: augmenting crystallographic analysis with computer modeling. J. Comput. Aided Mol. Des. 17, 525536 2003 ; . 12. Brik, A. et al. Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors. Chembiochem. 4, 12461248 2003 ; . 13. Schapira, M. et al. Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking. Proc. Natl Acad. Sci. USA 100, 73547359 2003 ; . 14. Evers, A. & Klebe, G. Ligand-supported homology modeling of G-protein-coupled receptor sites: models sufficient for successful virtual screening. Angew. Chem. Int. Ed. Engl. 43, 248251 2004 ; . 15. Shoichet, B. K., McGovern, S. L., Wei, B. & Irwin, J. J. Lead discovery using molecular docking. Curr. Opin. Chem. Biol. 6, 439446 2002 ; . 16. Schneidman-Duhovny, D., Nussinov, R. & Wolfson, H. J. Predicting molecular interactions in silico: II. Protein-protein and protein-drug docking. Curr. Med. Chem. 11, 91107 2004 ; . 17. Wyss, P. C. et al. Novel dihydrofolate reductase inhibitors. Structure-based versus diversity-based library design and high-throughput synthesis and screening. J. Med. Chem. 46, 23042312 2003 ; . 18. Kick, E. K. et al. Structure-based design and combinatorial chemistry yield low nanomolar inhibitors of cathepsin D. Chem. Biol. 4, 297307 1997 ; . 19. Doman, T. N. et al. Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B. J. Med. Chem. 45, 22132221 2002 ; . 20. Paiva, A. M. et al. Inhibitors of dihydrodipicolinate reductase, a key enzyme of the diaminopimelate pathway of Mycobacterium tuberculosis. Biochim. Biophys. Acta. 1545, 6777 2001 ; . 21. Gradler, U. et al. A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase. J. Mol. Biol. 306, 455467 2001 ; . 22. Powers, R. A., Morandi, F. & Shoichet, B. K. Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase. Structure Camb. ; 10, 10131023 2002 ; . 23. Gruneberg, S., Stubbs, M. T. & Klebe, G. Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation. J. Med. Chem. 45, 35883602 2002 ; . 24. Wei, B. Q., Baase, W. A., Weaver, L. H., Matthews, B. W. & Shoichet, B. K. A model binding site for testing scoring functions in molecular docking. J. Mol. Biol. 322, 339355 2002 ; . 25. Lipinski, C. A., Lombardo, F., Dominy, B. W. & Feeney, P. J. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 23, 325 1997 ; . 26. Oprea, T. I. Current trends in lead discovery: are we looking for the appropriate properties? Mol. Divers 5, 199208 2002 ; . 27. McGovern, S. L., Caselli, E., Grigorieff, N. & Shoichet, B. K. A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening. J. Med. Chem. 45, 17121722 2002 ; . 28. Krmer, O., Hazemann, I., Podjarny, A. D. & Klebe, G. Virtual screening for inhibitors of human aldose reductase. Proteins 55, 814823 2004 ; . 29. Horn, J. R. & Shoichet, B. K. Allosteric inhibition through core disruption. J. Mol. Biol. 336, 12831291 2004 ; . 30. Kaiser, J. NIH Gears up for chemical genomics. 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Common side effects include drowsiness, dizziness, confusion, anterograde amnesia, agitation, impaired coordination, increased daytime restlessness or anxiety. Metallic taste as zopiclone is secreted in saliva. Risk of dependence is increased if there is a history of alcoholism or drug abuse. CONTRAINDICATED in patients with severe respiratory dysfunction such as sleep apnea, for example, emtriva.
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Was plotted as a function of pulse-exposure time for several concentrations of each of the drugs, the relationships shown in Fig. 1, 2, and 3 were obtained. All of the drug concentrations employed were in excess of the MIC values, and similar multiples of the MIC were tested for each agent. The RMP Fig. 1 ; and SM Fig. 2 ; data show that at any fixed pulse-exposure time a doubling of the drug concentration results in an approximate doubling of growth inhibition. For example, 8-hr pulses with 0.0125, 0.025, and 0.05 , ug of RMP per ml resulted in 9, 18, and 37% growth.
There are many other medicines that can interact with sustiva, or make it less effective.
Prescription drug coverage This rider is optional at an additional cost with Century Preferred Direct and Century Preferred Direct HSA, included in BlueCare Direct HSA and cannot be deleted. ; Riders may be added at the time of enrollment. Riders can also be added once in a 12 month period and will be subject to underwriting approval. Riders will be deleted on the first of the month following notification. Deleted riders may not be re-added to the policy for 12 months.
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New drugs added since June 2002 indicated in bold. ANTIRETROVIRALS NRTIs- abacavir Ziagen ; , abacavir lamivudine zidovudine Trizivir ; , didanosine ddI, Videx, Videx EC ; , emtricitabine Emtriva ; , lamivudine Epivir, 3TC ; , lamivudine zidovudine Combivir ; , stavudine d4T, Zerit ; , tenofovir Viread ; , zalcitabine ddC, Hivid ; , zidovudine AZT, Retrovir ; . PIs- amprenavir Agenerase ; , atazanavir Reyataz ; , fosamprenavir Lexiva ; , indinavir Crixivan ; , lopinavir ritonavir Kaletra ; , nelfinavir Viracept ; , ritonavir Norvir ; , saquinavir Fortovase, Invirase ; . NNRTIs- delavirdine Rescriptor ; , efavirenz Suetiva ; , nevirapine Viramune ; . Other- hydroxyurea Hydrea ; . Entry Inhibitor- enfuvirtide Fuzeon ; . OI DRUGS PHS "A1 OI"s- acyclovir Zovirax ; , azithromycin Zithromax ; , cidofovir Vistide ; , clarithromycin Biaxin ; , famciclovir Famvir ; , fluconazole Diflucan ; , foscarnet Foscavir ; , itraconazole Sporonox ; , leucovorin Wellcovorin ; , pyrimethamine Daraprim ; , sulfadiazine, TMP SMX Bactrim, Septra ; . Other OIs- amphotericin B Fungizone ; , atovaquone Mepron ; , ciprofloxacin Cipro ; , clindamycin Cleocin ; , clotrimazole Lotrimin, Mycelex ; , dapsone, doxorubicin liposomal DOXIL ; , ethambutol Myambutol ; , filgrastim GCSF Neupogen ; , ketoconazole Nizoral ; , nystatin Mycostatin ; , pentamidine NebuPent, Pentam ; , primaquine, rifabutin Mycobutin ; , trimethoprim, valacyclovir Valtrex ; , valganciclovir Valcyte ; . Hepatitis C- none. TREATMENTS FOR METABOLIC DISORDERS Hyperlipidemia- artovastatin Lipitor ; , fluvastatin Lescol ; , gemfibrozil Lopid ; , lovastatin Mevacor ; , pravastatin Pravachol ; , simvastatin Zocor ; , Wasting- megestrol acetate Megace ; . ALL OTHERS amitriptyline Elavil ; , buproprion Wellbutrin SR ; , citalopram Celexa ; , fentanyl Duragesic ; , fluoxetine Prozac ; , gabapentin Neurontin ; , ibuprofen Motrin ; , loperamide Imodium ; , morphine sulfate MS Contin ; , nefazadone Serzone ; , paroxetine Paxil ; , polycarbophil Fibercon ; , psyllium Metamucil ; , sertraline Zoloft ; , trazodone Desyrel ; , venlaxafine Effexor ; . Vaccines- Hepatitis A, Hepatitis B, pneumococcal vaccines as outpatient treatment Pnemovax, Pnu-imune.
Q. Do you recall what you tried to do in terms of developing the record or witnesses to testify? A. Nothing at that point. There wasn't time to do it, except to wonder where his mother was. She indicated she would be back to ask Jason if he would like her to testify on his own behalf on the penalty phase. In view of this testimony and other substantial evidence presented at the postconviction hearing, including the testimony of two mental health experts, we believe that counsel's shortcomings were sufficiently serious to have deprived Deaton of a reliable penalty phase proceeding. Consequently, under the circumstances of this case, we must find that Deaton's counsel was ineffective and that such ineffective assistance was prejudicial. Deaton v. Dugger, 635 So. 2d at 8-9. Unlike the unanimous majority in Deaton, today's majority misreads Strickland to impose a burden on the defendant to prove that the result in his case would have been different, an almost impossible burden. The majority appears to have applied an erroneous new trial standard expressly rejected by the U.S. Supreme Court in its analysis. See Strickland, 466 U.S. at 693 "On the other hand, we believe that a defendant need not show that counsel's deficient conduct more likely than not altered the outcome in the case." ; . Under the correct standard, it is difficult, if not impossible, to conclude, as we did in Deaton, that our confidence in the outcome of this proceeding is not undermined by the incompetence of this counsel's representation and ethambutol, because aids.
Analysis of long-term data from study 006 median follow-up 180 weeks, 102 weeks, and 76 weeks for patients treated with efv + zdv + lam, efv + idv, and idv + zdv + lam, respectively ; showed that, beyond 24 weeks of therapy, the incidence of new-onset nervous system symptoms among patients treated with sustiva were generally similar to those in the indinavir-containing control arm.
The following artificial saliva substitutes to be prescribed only for indications approved by the acbs ; have been added to part xviia of the drug tariff dental prescribing ; : as saliva orthana, biotene oralbalance, bioxtra, glandosane, saliveze, salivix and myambutol.
Most of the new drugs over the past several years are primarily variants of old drugs.
00056047330 00056047492 00056051030 SUSTIVA SUSTIVA SUSTIVA NORVIR KALETRA KALETRA NORVIR VIDEX CAP 100MG CAP 200MG TAB 600MG SOL 80MG ML SOL CAP CAP 100MG SOL 4GM 2 105 $141.02 $39, 105.76 $71, 157.29 $1, 935.24 $3, 687.28 $136, 784.49 $14, 054.52 $717.02 $785.26 $248.36 $3, 922.86 $7, 136.10 $22, 312.09 $3, 645.69 $29.04 $73, 674.37 $599.96 $3, 060.47 $141, 555.65 $3, 332.89 $50, 471.86 $4, 221.26 $7, 281.54 $46, 312.48 $8, 227.85 $0.00 $0.00 0.08% 4.19% 7.18% 0.00% 0.00 and etoposide.
Procedures to assist or replace heart function: 1 ; intra-aortic balloon pump figure 152 ; , 2 ; permanent implantable balloon pump figure 153 ; , 3 ; total artificial heart figure 154.
Sustiva is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine hivid ; , zidovudine retrovir ; , didanosine videx ; , and and vepesid.
In 2004 our responsive mode success rates had decreased to 16% in our Research Grants scheme. In SR 2004 we prioritised sustained support for blue-skies responsive mode research. Two years on responsive mode success rates average 30%. Maintaining adequate levels of support in this area ensures the generation of novel research and the continued support of the academic sector as we establish ourselves as a Council and expand into new areas such as KT and strategic research. We've increased support for team-based responsive mode research from 75 to 80% of our responsive mode budget, because efavirenz.
PHOTO NOT AVAILABLE DUE TO EXPERIMENTAL STATUS CLASS: entry inhibitor--experimental CCR5 antagonist STANDARD DOSE: Not yet determinded. Once and twice daily doses being studied. MANUFACTURER CONTACT: Pharmacia and Upjohn Company, a Pfizer company, pfi zer , 1 212 ; 5731000 AIDSINFO: 1 800 ; HIV0440 4480440 ; , aidsinfo.nih.gov POTENTIAL SIDE EFFECTS AND TOXICITY: No maraviroc related liver damage or cancers found in studies. POTENTIAL DRUG INTERACTIONS: Aptivus Norvir had no interactions with maraviroc in healthy HIV-negitive ; volunteers. S8stiva reduced maraviroc concentrations by 50%, while Viramune and Kaletra increased maraviroc concentrations. The official dosing recommendations for these combinations will be known once the drug is approved. TIPS: Maraviroc is expected to go into expanded access free drug for people in medical need, before FDA approval ; this year; visit maraviroceap . Maraviroc is one of the truly new drugs that advanced patients are in so desperate need of--and it's not the only one, making 2007 an especially promising year see page 17 ; . But maraviroc is not without problems. One, it relies on tropism, and two, other drugs of its type have been discontinued or curtailed during development in late 2005--not a happy sign. Tropism refers to one of the types of HIV that a person can have: CCR5-tropic R5 ; virus and CXCR4-tropic X4 ; virus. HIV latches on to the CD4 receptor on the surface of some human cells hence, CD4 + cells ; , and then it latches on to one of the two co-receptors on the surface of the cells, CCR5 R5 ; or CXCR4 X4 ; . These two chemokine co-receptors basically invite HIV to come inside. As the name "CCR5 inhibitor" suggests, maraviroc inhibits blocks ; CCR5, shutting down this point of entry for the virus. The co-receptor inhibitors are also called "antagonists, " as in "CCR5 antagonist." ; X4 virus is associated with advanced HIV disease. HIV infection may involve viruses that infect only CCR5 cells, only CXCR4, both of these types of cells dual tropic ; , or a mix mixed tropic ; . Most people are infected with CCR5 virus and then over time more CXCR4 and mixed viruses accumulate. Results presented at 2006 IAS indicated that Pfizer did not fi nd that blocking R5 with maraviroc caused virus to shift to X4 or show any other negative effect in so-called "dual tropic" people their virus can use either R5 or X4 ; the other hand, viral load drops were not great, although better than placebo plus optimized therapy. That wasn't unexpected in this population, for which maraviroc is not aimed, but it's disappointing nevertheless. Remember that these people had virus that could use either R5 or X4 for entry to the cell, so that could be expected to blunt the response. T-cells, however, went up by about twice as much as with placebo dummy pill ; plus optimized background therapy around 60 v. 36 ; Coreceptor inhibitors are part of the HIV entry inhibitor class of drugs--they work in different ways to stop the virus from infecting the cell. People with genetically inherited absence of CCR5 receptors have been found to be highly resistant to HIV infection. Nevertheless, whether there are longterm effects of blocking this immune system chemokine receptor remain to be seen. The co-receptor antagonists hit the body's cells have a cellular target ; , which is exciting and is something to keep in mind for the future. A weird observation in genetically-altered mice was increased risk of West Nile virus. A test to measure tropism is available and may become important for co-receptor therapy and famciclovir.
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ANTIRETROVIRALS NRTIs- abacavir Ziagen ; , abacavir lamivudine Epzicom ; , abacavir lamivudine zidovudine Trizivir ; , didanosine ddI, Videx ; , emtricitabine Emtriva ; , lamivudine Epivir, 3TC ; , lamivudine zidovudine Combivir ; , stavudine d4T, Zerit ; , tenofovir Viread ; , tenofovir emtricitabine Truvada ; , zalcitabine ddC, Hivid ; , zidovudine AZT, Retrovir ; . PIs- amprenavir Agenerase ; , atazanavir Reyataz ; , fosamprenavir Lexiva ; , indinavir Crixivan ; , lopinavir ritonavir Kaletra ; , nelfinavir Viracept ; , ritonavir Norvir ; , saquinavir Fortovase, Invirase ; , tipranavir Aptivus ; . NNRTIs- delavirdine Rescriptor ; , efavirenz Xustiva ; , nevirapine Viramune ; . Other- hydroxyurea Hydrea ; . Entry Inhibitors- enfufuvirtide Fuzeon ; . OI DRUGS PHS "A1 OI"s- acyclovir Zovirax ; , azithromycin Zithromax ; , clarithromycin Biaxin ; , clindamycin Cleocin ; , famciclovir Famvir ; , fluconazole Diflucan ; , ganciclovir Cytovene ; , itraconazole Sporonox ; , leucovorin, pentamidine NebuPent ; , pyrimethamine Daraprim ; , rifabutin Mycobutin ; , sulfadiazine, TMP SMX Bactrim, Cotrim, Septra, Sulfatrim ; , valacyclovir Valtrex ; , valganciclovir Valcyte ; . Other OIs- atovaquone Mepron ; , ciprofloxacin Cipro ; , dapsone, ethambutol Myambutol ; , ketoconazole Nizoral ; , nystatin Mycostatin, Nilstat ; , paromomycin Humatin ; . ALL OTHERS amitriptyline Elavil ; , diphenoxylate Lomotil ; , lansoprazole Prevacid ; , loperamide Imodium ; , nortriptyline Pamelor ; , omeprazole Prilosec ; , ondansetron Zofran ; , pancrelipase Pancreas ; , prochlorperazine Compazine ; , promethazine Phenergan.
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Details of the projections mentioned can be found in a selection of text including the latest edition of Clark's Positioning in Radiography that should be the standard for techniques. Further information can be obtained in the following texts: A guide to Radiological Procedures by Chapman & Nakielny. Introduction to Pathology by Prime. Radiographic Positioning and Related Anatomy. by Bontrager Contrast Media literature from suppliers. Hospital Drug Administration Policy Document.
TABLE 2.1 Risk of HIV, HBV and HCV transmission from a known positive source and
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Almost all cases of pseudomembranous colitis reported during the past 3 decades have been associated with antimicrobial use. We report a case of nonantibiotic-associated pseudomembranous colitis and review similar cases in the literature that suggest the need for increased clinical awareness of this condition. A 77-year-old white female presented with a history of watery diarrhea, abdominal cramping, and a 30-lb weight loss during the past 6 weeks. She denied recent antibiotic use, which was confirmed by contacting her pharmacist. Colonoscopy revealed severe focal ulceration of the colonic mucosa and adherent yellow plaques in the rectum and sigmoid colon, pathologic features consistent with pseudomembranous colitis. The result of a stool cytotoxin assay was positive for Clostridium difficile. The patient was treated with oral vancomycin and exhibited rapid improvement. In a review of the literature, we found 9 well-documented cases of nonantibiotic-associated pseudomembranous colitis in patients without predisposing factors. Most of those patients were elderly women who presented with diarrhea and abdominal pain. The diagnosis of pseudomembranous colitis was confirmed by colonoscopy, by the identification of C difficile in stool culture, or by cytotoxicity assay. Treatment usually was initiated with oral vancomycin and dosages differed. In the 9 cases reviewed, the mortality rate was 11% and the rate of relapse, 33%. Adv Stud Med. 2003; 3 10 ; : 571-574 and tamsulosin and sustiva, for example, haart.
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As described in Part I, most types of bladder dysfunction will respond well to conservative treatment measures, particularly if begun early, before more serious problems have arisen. The options described here should generally be considered only for those patients in whom the more conservative measures have not been successful. Being able to document a conservative progression of interventions will make it easier to obtain insurance coverage should surgical procedures become necessary. To ensure the safety and success of complex surgical procedures, it is important to screen patients carefully. Treatment decisions should take into account the patient's weight and physique, level of disability and ability to function independently, cognitive impairment, manual dexterity, concurrent medical problems, social support networks, life expectancy of an additional 20 years or more, and urodynamic parameters. Only those who are able to comply reliably with and
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Overall, 100 percent of patients receiving dot responded and 94 percent of patients receiving sustiv plus 2 nrtis in the sat group responded through 48 weeks.
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For more information, see the booklet viral load & CD4 that forms part of this series and is produced by NAM. As a woman's health improves on antiretrovirals, her fertility may also increase. It is recommended that women considering pregnancy, or women who may conceive, discuss their treatment options with their doctor before conceiving. One reason for this is that some anti-HIV medicines e.g. efavirenz, Wustiva ; are not generally recommended for women who are planning a pregnancy. You should tell your HIV doctor or another member of your healthcare team immediately if you become pregnant. The contraceptive pill is less effective in women on many of the anti-HIV drugs due to drug interactions.
Regular exercise and a healthy diet may reduce the risk, because quickscreen.
SOTRADECOL [INJ] sotret SPACE CHAMBER spacol i.d. spastrin SPECTRAGEL SPIRIVA spironolactone, w hctz SPORANOX soln sprintec SPRYCEL sps oral susp SPS rectal sronyx ssd, af stagesic STAGESIC-10 STALEVO 100, 150, 50 stamoist e stanimax stannous fluoride STARLIX statuss dm STERILE DILUENT [INJ] STIMATE STRATTERA STREPTOMYCIN SULFATE [INJ] STROMECTOL strong iodine strovite, plus su-tuss dm, hd sublimaze [INJ] SUBOXONE SUBUTEX suclor SUCRAID sucralfate sudatex sudatuss dm SUDATUSS-2 SUDATUSS-SF sufenta [INJ] sufentanil citrate [INJ] SULAR sulfac sulfacetamide sodium, w-prednisolone sulfadiazine sulfamethoxazole-trimethoprim sulfamide SULFAMYLON sulfasalazine sulfatol sulfatrim sulfazine, ec sulindac sultrex supartz [INJ] suphera SUPPRELIN [INJ] SURE-T surgifoam SUSTIVA SUTENT symax, -sl, -sr SYMLIN [INJ] SYNAGIS [INJ] SYNAREL SYNERCID [INJ] syntest d.s., h.s. syrex [INJ] t-tanna dm TALWIN [INJ] TAMIFLU tamoxifen citrate tana dm, pse, r-12, t-12 tanacof xr tanatan rf tanatuss tanavan tannate, 12 s, 12d s, dmp-dex, -v-dm tannic-12, s tannihist-12 d, rf TARCEVA TARGRETIN TASMAR TAXOTERE [INJ] TAZICEF [INJ] TAZORAC taztia xt tbc TE ANATOXAL BERNA [INJ] tebamide TEGRETOL XR temazepam TEMODAR tencet tencon TENORMIN I.V. [INJ] TEQUIN inj terazosin, hcl terbutaline sulfate terconazole TERRAMYCIN, IM [INJ] tesamone-100 [INJ] TESLAC TESTOPEL [INJ] testosterone [INJ] TETANUS DIPHTHERIA TOXOIDS [INJ] tetcaine tetra tannate tetra-mag tetracaine hcl tetracycline hcl THALOMID theochron theophylline anhydrous THERACYS [INJ] thermazene therobec plus thiamine hcl [INJ] THIOCYL [INJ] THIOGUANINE thioridazine hcl thiotepa [INJ] thiothixene thrombogen THYMOGLOBULIN [INJ] THYREL TRH [INJ] THYROGEN [INJ] thyroid THYROLAR TICAR, IN DEXTROSE [INJ] TICE BCG [INJ] TIKOSYN TILADE TIMENTIN, ISO-OSMOTIC [INJ] timolol maleate tis-u-sol tizanidine hcl tobramycin sulfate tobramycin sulfate in ns [INJ] tobrasol tolazamide tolbutamide tolmetin sodium TOPAMAX toposar [INJ] TOPROL XL [G] * TORADOL [INJ] torsemide TPN ELECTROLYTES II [INJ] TRACE ELEMENTS [INJ] TRACE METALS [INJ] TRACLEER tramadol hcl, -acetaminophen tranylcypromine sulfate TRAVASOL, W DEXTROSE [INJ] TRAVERT [INJ] trazodone, hcl TRELSTAR DEPOT, LA [INJ] tretinoin TREXALL tri-a-vite w fluoride TRI-CHLOR tri-hist tri-histine TRI-K tri-otic tri-previfem tri-sprintec TRI-VENT DM tri-vent dpc tri-vit w fluoride & iron triam forte [INJ] triam-a [INJ] triamcinolone acetonide triamterene w hctz triazolam TRICHLOROACETIC ACID tricitrates tricof tricon TRICOR tricosal tridal hd, plus triderm trifluoperazine hcl trifluridine trihexyphenidyl hcl TRIHIBIT [INJ] TRILEPTAL trimethobenzamide hcl cap, rectal TRIMETHOBENZAMIDE HCL inj trimethoprim trimipramine maleate trimox 125 trinate trinessa trionate, nf TRIOSTAT [INJ] triotann, -s TRIPEDIA [INJ] triple antibiotic, tannate pediatric TRISENOX [INJ] trital dm TRITUSSIN trivora-28 and vaseretic.
The second would be teenagers or young adults, who found out rather quickly that if the pill was crushed and snorted, or cooked and injected, that it provided a high that was just as good as or even better than heroin.
F Paternal cantly affect fetal weight 30-, from 0-mg kg cocaine administration did not signifior differ the number of implants, Table 3 ; . Ad libitum animals animals in any of these resorptions did not.
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Sustiva had 2004 sales of $621 million.
SNF-report No. 20 05 2005 ; . Marketing contracts for salmon in China might therefore be based on contracts made in the head office in a supermarket chain in Paris, not in China. It means that business performances in the seafood trade pattern are dependent on the connections in the value chain between the different internal functions in seafood firms and between the seafood firms from fishing or aquaculture to the final fish consumers of the end product. A value chain can be described as a line of transactions, where product and services are flowing and transformed from the living fish through harvesting, processing and transporting to the final users and consumers. This flow has a compensation flow of payment from the end users and consumers to the input suppliers. The engine in this flow is according to trade theory the value adding carried out by the participants involved in the transactions throughout the chain for overview see for example Cateora, 1987 ; . Such chains might be loosely coupled, meaning that the participants make their contracts on a case by case basis, or strongly connected in long term contracts which include several units in the chain. The value chain can be illustrated as a chain of wagons carrying participants in a moving train, where each participant has a direct view to its supplier on the input side and to the customer on the customer side, but where both the supplier and the customer are part of the same moving train. If we map the direction and the forces driving the train, we also know a lot about the behaviour of the participating firms. Some of these value chains are very profitable, others less. The profitable chains will attract participants who want to take part in the value adding. Those who already are in the chain will try to protect the value adding by building barriers making it difficult for new entrants to get onboard Porter 1980 ; . The theory anticipates that there are some competition factors which are common in value chains differentiated by type of products, technology, markets etc. In the seafood business such chains can be identified by type of fish species for example cod and salmon ; , type of processing technology for example fresh and frozen products ; , and business focus for example cost orientation or market orientation or kind of market focus for example export or domestic marketing ; . Parts of the value chain may also be characterized as strategic groups, for example freezing vessels, exporters, importers, processors and marketers. Each of these strategic groups has also some competition rules in common which strongly influence the performance for the firms involved Barney 1997 ; . Figure 7 adopts the SCP model for analysing performance on a value chain level. The model anticipates that performances in value chains are dependent on the conducts of the firms in the value chain and the conducts are dependent on the value chain context see, for example, .