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What is a Percutaneous Coronary Intervention PCI ; ? continued ; Stent: The cardiologist places a small, hollow metal mesh ; tube called a "stent" in the artery to keep it open following a balloon angioplasty. The stent prevents constriction or closing of the artery during and after the procedure. Drugeluding stents are now used. These stents are coated with medication that helps prevent narrowing of the artery. Coronary Artery with Stent, for example, coumadin.
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| History of VasereticSir, We are aware of the data referred to by Dr Jolobe, but must point out that very few of these are from prospective randomised controlled trials. The notable exception is CHARM-Preserved, 1 but even in that trial, the active treatment did not reduce the risk of the predefined primary outcome. Non-randomised and retrospective analyses are unreliable and should not be used as a basis for the recommendation of a treatment. That is why there is no treatment specifically for heart failure with preserved ejection fraction recommended in any evidence-based guideline. Of course, atrial fibrillation, hypertension and coronary heart disease should be treated as appropriate in these patients. John McMurray, 1 Gareth Padfield and myambutol, for example, ibuprofen.
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HULLEY S et al: Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen progestin Replacement Study HERS ; Research Group. JAMA 280: 605, 1998 MANSON JE, MARTIN KA: Clinical practice: Postmenopausal hormone-replacement therapy. N Engl J Med 345: 34, 2001 NELSON HD et al: Postmenopausal hormone replacement therapy: Scientific review. JAMA 288: 872, 2002 WRITING GROUP FOR THE PEPI TRIAL: Effects of estrogen or estrogen progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen Progestin Interventions PEPI ; Trial. JAMA 273: 199, 1995 WRITING GROUP FOR THE WOMEN'S HEALTH INITIATIVE INVESTIGATORS: Risks and benefits of estrogen plus progestin in healthy postmenopausal women. Principal results from the Women's Health Initiative randomized controlled trial. JAMA 288: 321, 2002 and etoposide.
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Keratolytic agents induce sloughing of cornified epithelium.1 Keratolytics cause peeling of the skin by softening and destroying the stratum corneum by increasing endogenous hydration. This in turn causes the cornified epithelium of the skin to swell, soften, and then desquamate.1, 2 In normal skin with more than 10% hydration, the stratum corneum is a "wall" composed of stacked layers of comeocytes held together by a lipid-based intercellular matrix that serves as a tough yet flexible protective barrier against excessive water loss.2 When the water content is less than 10%, disruption in the stratum corneum can occur, leading to scaling, cracking, and irritation, and resulting in skin disorders, such as xerosis, ichthyosis, and psoriasis. Xerosis, or excessive dryness of the skin, is characterized by redness, dry scaling, and fissures.2 Xerosis occurs when there are abnormalities in the structure of the stratum corneum due to keratinization, proliferation, surface lipids, water metabolism, pH changes, and sebum. Ichthyosis is a hyperkeratotic skin disorder, characterized by dry and scaly skin that resembles the scales of a fish.2, 3 Psoriasis is associated with well-defined plaques bearing adherent, silvery scales.1, 4-5 The skin and mucous membrane keratolytic agents that are included in this review are listed in Table 1. This review encompasses all topical ; dosage forms and strengths. Products solely indicated for the treatment of acne and or rosacea are considered cosmetics, and are not covered by Alabama Medicaid; hence, these products are not included in this review.
Autoantibody RF ANA Disease RA 80% Sjgren's 50% SLE 95% other CTDs e.g. RA, PSS ; SLE 30-70% SLE 30% Sjgren's 75% SLE 25 % Sjgren's 40% SLE 10% APS SLE 31-40% Drug-induced SLE 90% idiopathic SLE 50% MCTD CREST 80% PSS 26-76% Active Wegener's 90% Wegener's 10%, other vasculitis 0% 0% 0% 0% 0% Specific and sensitive Normals 5% Comments and
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Sir, Fibreoptic bronchoscopy is often helpful in the diagnosis of lung cancer with a tissue diagnosis often achieved by endobronchial biopsy of visible tumour. The BTS guidelines on flexible bronchoscopy recommend a diagnosis rate of at least 80% when there is visible endobronchial tumour.1 The diagnostic yield for malignancy from biopsy in the presence of suggestive findings has been reported as 82% in a recent study.2 Clinically significant greater than 50 mls ; bleeding occurred in 19% of biopsies in one large review of bronchoscopies, 29% of these following endobronchial biopsy. Profuse bleeding greater than 100 mls ; occurred in 04% of biopsies, 25% of these following endobronchial biopsy.3 More vascular tumours are associated with higher incidence and severity of bleeding, and the quoted risks of bleeding in the above studies would be expected to be higher following biopsy of larger and more vascular tumours. Once significant bleeding during endoscopy occurs, it can be difficult to take further biopsies and control the site of bleeding. Electrocautery uses alternating current at high frequency to generate heat to coagulate, vaporise or cut tissue depending on the power; 4 its use is established in colonoscopic hot biopsy, and palliation of upper airway obstruction or haemoptysis at bronchoscopy.5 We used electrocautery in a case series of 34 patients over 12 months with endobronchial tumours with more vascular appearance which might have been predicted to bleed more than others following biopsy. Electrocautery was applied in a controlled fashion prior to biopsy without obliterating the tissue integrity but sufficient to be more confident of haemostasis after biopsy. No significant bleeding occurred and there were no major complications relating to the use of electrocautery. The diagnostic yield was 882% which compared favourably with our units histological yield unpublished observations ; without electrocautery in the presence of tumour. This technique may be particularly helpful when trying to biopsy more vascular tumours by minimising bleeding while not adversely affecting yield at least one major bleed requiring ITU and famciclovir.
A wide range of non-pharmacological interventions has been tested in behaviourally disturbed people with dementia. Many of the trials have had significant methodological limitations. Nevertheless, a recent systematic review found that there was evidence to support the efficacy of activity programs, music, behaviour therapy, light therapy, carer education and changes to the physical environment.2 In well-run residential aged-care facilities some of these techniques are in routine use. Interventions for patients with dementia and behavioural problems should be individualised. Specific discussion of this complex issue is contained in a report to the Commonwealth Department of Health and Ageing on the psychosocial approaches to challenging behaviour in dementia.3, because zocor.
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ESTABLISHMENT AND VALIDATION OF AN ENZYMELINKED IMMUNOSORBENT ASSAY FOR THE QUANTIFICATION OF IMMUNOGLOBULIN A IN FECAL SAMPLES FROM DOGS. U Tress, JM Steiner, CG Ruaux, and DA Williams. Gastrointestinal Laboratory, College of Veterinary Medicine, Texas A&M University, College Station, TX. Mucosal surfaces, such as the gastrointestinal mucosa, can be the point of entry for a variety of pathogens. Secretory IgA is the predominant immunoglobulin subtype in mucosal secretions and is believed to protect mucosal membranes from the entry of pathogens. In human beings IgA deficiency is the most common primary immunodeficiency and is associated with frequent infections of the gastrointestinal, respiratory, and urogenital tracts. A comparable disorder has been reported in certain dog breeds, such as German Shepherd Dogs. In human beings IgA deficiency is defined by the presence of a low serum IgA concentration. In dogs, however, it is reported that serum IgA concentrations do not reflect local intestinal IgA production German et al, Vet Immunol. Immunopathol. 76: 2543 ; and measurement of fecal IgA concentrations might be more meaningful. Therefore, the goal of this study was to establish and validate a method for measurement of IgA concentrations in fecal samples from dogs. Immunoglobulin A was extracted from canine fecal samples, taken from the first bowel movement of the day. A sandwich ELISA was established for the measurement of IgA concentrations in these extracts. The assay was validated by determination of sensitivity, linearity, accuracy, precision, and reproducibility. Commercially available goat anti-dog IgA antibodies served as primary and secondary antibodies, with the secondary antibody being biotinylated. Commercially available dog IgA reference serum of known IgA concentration was used to prepare a range of standards. A reference range was determined from the mean IgA concentration of four fecal samples from 18 clinically healthy dogs by calculating the central 95th percentile. The sensitivity of the assay was 0.06 mg g feces. Observed to expected ratios for dilutional parallelism of four fecal samples ranged from 109.7 - 119.8%. Observed to expected ratios for spiking recovery of the same samples ranged from 55.6 - 99.3%. The coefficients of variation for intra-assay and inter-assay variability and
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Is any general principle deducible from the foregoing catalogue of instances? Certainly, it cannot be said that, in general, where mens rea is an ingredient of an offence and the actus reus is proved it is enough if an intent is shown that would support a conviction of another crime, whether more or less serious than the offence actually committed. Coming to the particular, to the case before this Court, where proof is made of an actus reus that, in a general sense, is common to a range or variety of offences which require mens rea but those offences differ as to gravity by reason of different classifications and different penalties, is a charge of a more serious offence established by proof only that the accused intended to commit and could have been found guilty of a less serious, a lesser offence? The matter, in terms of principle, depends on how strict an observance there should be of the requirement of mens rea. If there is to be relaxation of the requirement, should it not come from Parliament, which could provide for the substitution of a conviction of the lesser offence, in the same way as provision now exists in our criminal law for entering a conviction on an included offence? This position is the one taken by the Model Penal Code of the American Law Institute 1962 ; which provides as follows in s. 2.04 2.
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Took place without delay, the little patient's condition deteriorated dramatically, as seen by signs of respiratory insufficiency, increase of heart rate and cyanosis. She was artificially respirated and transferred to the paediatric intensive care unit of a large hospital. On arrival, a decompensated respiratory acidosis with a pH of 7.2 was already found to be present. Chest X-ray revealed extended accumulation of fluid in both lungs, with pleural effusion right in the sense of an extended chemical pneumonia. In the further course, the clinical picture showed a pronounced acute respiratory distress syndrome ARDS ; which developed shortly afterwards. In spite of massive measures of intensive medical care, no oxygen saturation could be achieved even at the highest ventilation pressure available. After a sudden decrease of the heart rate followed by cardiac arrest, cardiac massage, intratracheal administration of three doses of adrenaline and defibrillation remained unsuccessful. The child died after ca. twelve hours from the sequelae of lamp oil aspiration, having developed a severe pneumonia and destruction of lung tissue, which were confirmed histologically. Evaluation of the case described: Based on the information received on the temporal relationship between ingestion and manifestations, a causal relationship is probable. Case No 2: Oil lamp A boy aged 20 months drank an unknown amount of a colourless and unscented paraffin-containing oil from a lamp a heavy glass bottle equipped with a metal ring that reportedly had held a wick ; . However, it has also been considered as possible that the boy had only sucked from the wick because the latter was found beside the bottle. The lamp had been placed on the terrace. The manufactur and
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Medicare is taking advantage of new technology available. For fee schedule year 2005, our office will be mailing out the Locality Fee Schedule Reports via CD-ROM. The CD-ROM version will have the Locality Fee Schedule Reports in multiple formats for user friendliness, along with many other features. This will be geared so that offices will be able to utilize the CD-ROM as a training tool and as a resource. Some features that will be able to be found are: Enrollment Information, including the CMS-855 forms Previously published newsletters October 2003 to October 2004 HIPAA Information A listing of Local Medical Review Policies LMRPs ; Local Coverage Determinations LCDs ; Articles written by our Medical Review Staff clarifying special topics September 2004 P-04-3 ; Communiqu Kansas Nebraska Northwestern Missouri 129.
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