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Panel 1. Treatment options for hay fever5 Intermittent mild symptoms Intermittent or regular oral antihistamines are a good first choice. Intranasal antihistamines have a faster onset of action. Intermittent moderate to severe symptoms Intermittent or regular oral or intranasal antihistamines. Intranasal corticosteroids or decongestants ease nasal congestion. Intranasal decongestants can be used short-term to relieve congestion and allow penetration of an intranasal corticosteroid. Persistent moderate to severe symptoms Intranasal corticosteroids are the first-choice treatment. Intranasal decongestants can be used short-term to relieve congestion and allow penetration of an intranasal corticosteroid. If symptoms remain uncontrolled, increase the corticosteroid dose or use a different one. If itching and sneezing are troublesome, an antihistamine can be used. If watery rhinorrhoea is the predominant symptom, try intranasal ipratropium. If symptoms continue to be poorly controlled, consider a short course of oral corticosteroids. If eye symptoms predominate Oral antihistamines can be taken intermittently or regularly. Intraocular antihistamines are an alternative and act more rapidly; they may be preferable for intermittent use. Intraocular sodium cromoglicate can also be used for prophylaxis of persistent eye symptoms. If this is ineffective, try nedocromil or lodoxamide. NB: PRODIGY'S classification of allergic rhinitis is: Intermittent -- symptoms occur less than four days a week or for less than four weeks Persistent -- symptoms occur more than four days per week and for more than four weeks Mild -- symptoms are not troublesome and normal activities, such as sleep, sport, leisure, work and school, are unaffected Moderate -- symptoms are troublesome and one or more of the following occur: impairment of normal activities, such as sport, leisure, work and school; disturbed sleep. symptoms.7 Patients should be warned that antihistamine eye drops can cause local irritation and blurring of vision.7 The approach to treatment shown in Panel 1 can be helpful when considering options see Table 1 for the relative effects of agents on symptoms ; . If maximal medication appears to be ineffective, the patient's compliance should be checked. In patients with severe symptoms or on special occasions e.g. when sitting examinations ; it may be worth considering a short course of oral corticosteroids.5 Oral corticosteroids are preferred to depot corticosteroids, as the dose of depot preparations cannot be tailored to the severity of symptoms. In addition, morning dosing with an oral corticosteroid may be less likely to cause adrenal suppression than continuous release from a depot injection.5 Referral to a specialist may be necessary in some patients. What is available over the counter? A wide range of OTC medication is available for managing allergic rhinitis symptoms, including representatives of most of the above.
Senate Committee on Health and Human Services C C identify the controlled substance prescribed; write the quantity of controlled substance prescribed, shown numerically and followed by the number written as a word; C identify the intended use of the controlled substance or the diagnosis for which it is prescribed and the instructions for use of the substance, unless it is contraindicated due to the patient's health status; C identify the practitioner's name, address, department registration number, and Federal Drug Enforcement Administration number; C the name, address, and date of birth or age of the person for whom the controlled substance is prescribed; and C not write more than one prescription on an official prescription form.40.

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UNH.N UnitedHealth Group ; : Solid 3Q05 Results Set the Bar Managed Care: FAS-123R Option Expense: Quantifying the Impact on 2006 EPS Projections Managed Care: Hewitt's "Same Bucket" Final Round: Gross Rates Decelerating 2% Managed Care: Little Clarity on Budget Reconciliation UnitedHealth Group UNH.N ; : Investor Day Highlights Managed Care: PDP Could Exceed Expectations -- It's Still Early Managed Care: 3Q Wrap-up: Approaching Year-end with Decelerating Trend Managed Care: Harris Poll: More Evidence of Higher Than Projected PDP Enrollment Entering 2006 Managed Care: Update on Budget Reconciliation & Implications for Managed Care Managed Care: Where to Steer in the New Year. Cialis online natural celebrex klebsiella spp and desyrel. 1. erowid experiences exp ?ID 1959 2. Berman, R. M., Narasimhan, M. & Charney, D. S. Depress. Anxiety 5, 154164 1997 ; . 3. Zarate, C. et al. Arch. Gen. Psychiatry 63, 856864 2006 ; . 4. Berman, R. M. et al. Biol. Psychiatry 47, 351354 2000 ; . 5. Abi-Saab, W. M., D'Souza, D. C., Moghaddam, B. & Krystal, J. H. Pharmacopsychiatry 31 Suppl. 2 ; , 104109 1998 ; . 6. Sonkusare, S. K., Kaul, C. L. & Ramarao, P. Pharmacol. Res. 51, 117 2005 ; . 7. Kugaya, A. & Sanacora, G. CNS Spectrums 10, 808819 2005 ; . 8. Trullas, R. & Skolnick, P. Eur. J. Pharmacol. 185, 110 1990 ; . 9. Sanacora, G. et. al. Arch. Gen. Psychiatry 61, 705713 2004 ; . 10. Zarate, C. A. et al. Am. J. Psychiatry 163, 153155 2006 ; . 11. Lilly, J. C. The Scientist: A Metaphysical Autobiography Ronin, Berkeley, CA, 1996. 4.11 Drugs for dementia Specialist Initiation Only Donepezil hydrochloride Galantamine Rivastigmine 5. INFECTIONS and famvir.
Staff Surveillance Surveillance for influenza-like illness among staff should be done during the influenza season. All staff should be aware of early signs and symptoms of respiratory disease. Staff shall be asked to report their respiratory illness to their supervisor or Employee Health. The supervisor or Employee Health shall inform the ICP of significant staff respiratory illness. Self Screening by Visitors, Family Members, Community and Professional Groups, Contractors, etc. All persons carrying on activities within the facility must self screen based on the signage posted and exclude themselves from entering the facility when feeling unwell. Hand washing facilities and or hand hygiene products are to be made available throughout the facility for use by all persons entering the facility. Surveillance processes are to be posted and followed by all entering the facility. Methods of Surveillance Daily surveillance is the most effective way to detect respiratory infections. There are two methods to conduct daily surveillance: active and passive. Passive Surveillance Passive surveillance involves looking for infections while providing routine daily care or activities. Residents with respiratory and other symptoms should be noted on the daily surveillance form. This form should be easy to use and include patient identification and location, date of onset, a checklist of relevant signs and symptoms, including fever, diagnostic tests and results when available. The completed form should be forwarded to the ICP on a daily basis. Any suspected outbreak should be reported immediately to the ICP. It is important to maintain a high index of suspicion for respiratory infections, especially during flu season, for example, cialis lilly.

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David Mabry Energy Management Specialist Letterkenny Industrial Development Authority - PA P.O. Box 1166 Harrisburg, PA 17108-1166 Fedex Address: 100 Pine Street Harrisburg, PA 17101 David Mabry Energy Management Specialist MeadWestvaco Corporation P.O. Box 1166 Harrisburg, PA 17108-1166 Fedex Address: 100 Pine Street Harrisburg, PA 17101 Bruce E. Campbell Sr. Manager, Regulatory Affairs Mirant Potomac River, LLC 8301 Professional Place Suite 230 Landover, MD 20785 Fedex Address: 8301 Professional Place Suite 230 Landover, MD 20785 Steve Jeremko ISO Regulatory Specialist NYSEG Solutions, Inc. P.O. Box 5224 Binghamton, NY 13902-5224 Fedex Address: James A. Carrigg Center 18 Link Drive Binghamton, NY 13902 and imovane. Mechanism of complement activation during I R in mouse models. The structures to which this IgM binds to the ischemic cells are, however, not known. We further investigated the specificity of the IgM binding to the damaged cells. First, we established that the level of IgM that bound to cells varied considerably among healthy donors. Inhibition experiments revealed that part of the IgM was directed against phosphorylcholine PCh ; , the head group of certain phospholipids, that are constituents of the cell membrane. The relative contribution of anti-PCh IgM to the total amount of IgM binding to the cells also varied among donors, ranging from 80% to virtually zero.Apparently, the specificity of IgM that binds to damaged cells differs greatly among individuals. To further verify the nature of the IgM antibodies, we developed an assay for anti-PCh IgM. Levels of this IgM in healthy donors, for instance, purchase cialis.
Sultants Inc, Trumbull, Conn David O. Cook, MD Piedmont Medical Research Associates Inc, Winston-Salem, NC Jeoffrey Deeths, MD Nebraska Clinical Research Center, Omaha, Neb Craig F. Donatucci, MD Duke University Medical Center, Durham, NC Mostafa M. Elhilali, MD Royal Victoria Hospital, Montreal, Quebec Pamela I. Ellsworth, MD Dartmouth Hitchcock Medical Center, Division of Urology, Lebanon, NH Howard B. Epstein, MD University of Florida, Jacksonville, Health Science Center, Jacksonville, Fla Robert A. Feldman, MD Urology Specialists, PC, CT Clinical Research Center, Waterbury, Conn Louis Fields, MD Thornhill, Ontario Roger Fincher, MD Spokane, Wash William Fitch III, MD Urology Consultants, PA, San Antonio, Tex Jenelle E. Foote, MD Midtown Urology, Atlanta, Ga Jeffrey Frankel, MD Seattle, Wash Harold A. Fuselier, MD Ochsner Foundation Hospital, Ochsner Clinic, Department of Urology, New Orleans, La Larry I. Gilderman, DO University Clinical Research Associates Inc, Pembroke Pines, Fla Marc Gittelman, MD South Florida Medical Research, Aventura, Fla Evan Goldfischer, MD Hudson Valley Urology Center, Poughkeepsie, NY James E. Gottesman, MD Seattle Urological Associates, Seattle, Wash Fred Govier, MD Virginia Mason Medical Center, Department of Urology, Seattle, Wash Michael Greenspan, MD Hamilton & District Urology Association, Hamilton, Ontario Wayne J. Hellstrom, MD Tulane University Medical Center, New Orleans, La Charles B. Herring, MD New Hanover Medical Research Associates, Wilmington, NC Gary S. Karlin, MD Lawrenceville Urology, Lawrenceville, NJ Joel M. Kaufman, MD Urology Research Options, Aurora, Colo Robert J. Krane, MD Massachusetts General Hospital, Department of Urology, Boston, Mass John N. Krieger, MD A Puget Sound Health Care System, Section of Urology, Seattle, Wash Alan Lau, MD University of Illinois at Chicago, Chicago, Ill William A. Leitner, MD Urology Centers of Alabama, PC, Birmingham, Ala Joel Lilly, MD Seattle Urological Associates, Seattle, Wash Jack Lubensky, MD Radiant Research Inc, Center for Clinical Research, Austin, Tex Nizamuddin Maruf, MD MidAtlantic Clinical Research Center, Rockville, Md Keith Matthews, MD Uromed, Montreal, Quebec Andrew McCullough, MD New York University Medical Center, Urology Research, New York, NY Kevin T. McVary, MD Northwestern Center for Clinical Research, Chicago, Ill Arnold Melman, MD Montefiore Medical Center, Department of Urology, Bronx William B. Monnig, MD The Urology Group, Cincinnati, Ohio Craig Niederberger, MD University of Illinois at Chicago, Chicago, Ill Harin Padma-Nathan, MD The Male Clinic, Beverly Hills, Calif Allan B. Patrick, MD Fredericton, New Brunswick Jon Lee Peterson, MD Health Advance, nTouch Research, Houston, Tex Peter J. Pommerville, MD Victoria, British Columbia V. Gary Price, MD North Texas Clinical Research, Fort Worth, Tex George Raad, MD Metrolina Medical Research Associates, Charlotte, NC Paul R. Sieber, MD Urological Associates of Lancaster, Lancaster, Pa Alan W. Skolnick, MD Health Advance Touch Research, Houston, Tex Christopher P. Steidle, MD Northeast Indiana Research, Fort Wayne, Ind Cecile Storrie, MD MDS Harris Inc, Dallas, Tex David Talley, MD Urology San Antonio Research, PA, San Antonio, Tex Joseph J. Tepas, MD University of Florida, Jacksonville Health Science Center, Jacksonville, Fla Timothy S. Truitt, MD Health Advance Institute, Melbourne, Fla Luc Valiquette, MD Hopital St Luc, Montreal, Quebec Alexander Vukasin, MD Urology Group of Princeton, PA, Princeton, NJ Mitchell Wiatrak, MD Midwest Research Specialists, Milwaukee, Wis John Williams, MD University of Florida, Jacksonville Health Science Center, Jacksonville, Fla Rafael Wurzel, MD Grove Hill Medical Center, New Britain, Conn Joseph Zadra, MD Barrie, Ontario ; . The authors thank Kenneth Pomerantz, PhD, and Helene Dassule, PhD, ` for editorial assistance and lasix.
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Every day in clinics and doctors' offices across the country, healthy middle-age women slide their wrists into portable X-ray machines that calculate bone density. If they get a low enough density score, they walk out with a prescription that's supposed to prevent a hip fracture late in life by adding bone tissue now. But there's a big problem with this familiar exercise, according to some top osteoporosis experts: Most of these women don't need the drug. They are wasting money and risking side effects for little benefit. "If you're a healthy 50-year-old -- an average woman going through menopause -- your chances of getting a fracture . are very low, " said Dr. Susan Ott, a bone specialist at the University of Washington. "Yet they are pushing the drug right at that age group." By targeting women in their 50s, manufacturers of drugs for osteoporosis have helped transform osteoporosis from an underrecognized disease in elderly women into what some say is a disease affecting tens of millions. Drug companies and advocacy groups accomplished that by: Expanding the disease to include a new condition, osteopenia, or pre-osteoporosis, with boundaries so broad they include more than half of all women over 50. Promoting osteopenia and osteoporosis directly to these younger, healthier women, telling them they are at risk and should consider taking bone-strengthening drugs such as Fosamax. Shaping the way osteoporosis and osteopenia are defined, with readings from bone-density machines that the drug industry promoted, subsidized and helped put in doctors' offices. All of this was done in the name of prevention. But Dr. Steven Cummings, one of the world's experts on osteoporosis and the director of the San Francisco Coordinating Center, a research center, says the drug companies' push has been driven by marketing as well as medicine. "The word `prevention, ' which has become so popular, has also created problems, " Cummings said. "Drug therapy for women with osteopenia does do some good because it reduces the risk of spine fractures, but women with osteopenia have a low risk of those fractures "So taking a drug for osteopenia probably does not improve the quality of life for women with osteopenia. It does generate huge sales." For elderly women who suffer fractures, bone drugs such as Fosamax are life-enhancing: strengthening bone, reducing chances of future breaks. The bone-density X-ray machines promoted by Merck & Co. and other drug companies also are powerful advances in treating the disease. Doctors can use them to diagnose those truly at risk and track their recovery. But, as Cummings points out, the utility of the machines and the drugs for middle-age women is unproven, unless they've had fractures previously. Their growing use is another cautionary tale of the influence of drug companies on the definition and treatment of disease. Even a former lobbyist for Merck concedes that the company's focus has been on expanding the market for Fosamax, also known by its chemical name, alendronate. "The goal is to make the uses as broad as humanly possible, " said Kurt Furst, who worked for Merck from 1997 to 2000. "Merck would tell you virtually any woman post-menopausal should go on Fosamax. That's a heck of a lot of women." By focusing on women 50 and older, Merck is following what other health organizations recommend, a company spokesman, Skip Irvine, said and levitra.

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Also establishing direct links to Chinese, Indian, and South African universities. Prevention, Treatment, and Surveillance Through funding from Lilly: Harvard University Partners in Health has established an MDR-TB research and training program in Tomsk, Russia. As a part of the training, health care workers from Russia and other countries of the former Soviet Union with high burdens of MDR-TB were trained in treating the illness, while research data obtained are being used globally to improve and potentially develop new treatments. The first class completed training in January 2004 and additional classes were held during 2004-2005. The training course received official accreditation by the Russian Ministry of Health in 2004. The International Council of Nurses has published TB and MDR-TB treatment guidelines for nurses around the world, launched in May 2004. The format is a pocket version specifically tailored to provide practical clinical guidance on how to prevent and treat TB and MDR-TB. A particular focus of this publication is prevention of drug resistance and management of side effects, which often are responsible for patients' abandoning the treatment process. CDC developed a laboratory-based electronic surveillance system to monitor resistance to drugs used for treating MDR-TB in Russian patients. The WHO has developed software to standardize data collection of patient outcomes at Green Light Committeeapproved treatment sites. Strengthening of data management will assist in improving logistics, training, and drug management i.e., better forecasting of drugs needed at treatment sites ; . Studies conducted in 2004 also verified the cost-effectiveness of the WHO's efforts to treat MDR-TB in the Philippines and Russia. The World Medical Association, in close collaboration with TB experts, WHO and national health organizations, is developing a physicians' distance-learning course on clinical management of TB and MDR-TB. The International Hospital Federation is drafting a syllabus for training hospital managers on the managerial and policy aspects of TB prevention and control. The International Federation of Red Cross and Red Crescent Societies IFRC ; is developing communication plans to reduce stigma and discrimination associated with TB. The IFRC volunteers will also provide psychological support and care assistance for homebound patients, to ensure that patients comply with treatment protocols designed by TB specialists. Lilly is pleased with the continuing progress of this partnership and believes that it will improve health care worldwide while establishing a model for bringing together public and private organizations to address global public health threats.

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INITIAL APPLICATION Applications only from a relevant specialist. Approvals valid for 3 years. Prerequisites tick boxes where appropriate. Rechen complex has changed several times; the conditions under which pharmaceutical and galenic products are manufactured have also undergone a major evolution. Nowadays the pharmaceutical manufacturing environment is governed by Good Manufacturing Practice GMP ; . Recently Vifor International ; once more showed compliance with GMP when Venofer successfully passed a preapproval inspection by the US Food and Drug Administration FDA ; in the autumn of 2000. 2.5. EMG recordings EMG activity of the left and right Flexor digitorum supercialis was recorded. Paired AgAgCl electrodes Vickers ; , 12 mm in diameter, were xed 2 cm apart on the skin over the forearm muscle, which was located by palpation. The EMG activity was continuously monitored, amplied Grass P5 AC ampliers, gain 5000 ; , ltered 10 Hz1 kHz ; and digitized on-line A D rate 2 kHz ; . 2.6. Adjustement trials Before the experiment, computer-piloted series of ``adjustment'' trials were performed to adjust the intensity of TMS stimulation for each subject individually. The intensity was adjusted to be high enough to produce observable MEPs, but suciently low that the stimulus artifacts directly induced in the recordings by the electromagnetic pulses see Section 2.8 ; did not last long enough to overlap with the MEPs. During each series of adjustment trials, the subject was asked to relax and received 16 stimulations delivered in a pseudo-random temporal sequence. After the last stimulation of a series, the electromyographic signal, averaged over the trials and timelocked to the occurrence of the stimulation, was displayed on the computer screen to be visually examined. The experiment began when an MEP was clearly apparent in the average and was completely separated in time from the stimulus artifact. 2.7. Design A block consisted of 96 experimental trials preceded by four warm-up trials. All precues provided valid information about the upcoming response signal. The three precues hand, FI, NI ; could be followed by a response signal indicating any of the four responses, yielding 12 behavioral conditions. There were six conditions of stimulation. Five of these conditions were dened by the time at which the TMS was delivered: 1000, 500, 333, or 0 ms prior to the response signal. In the sixth condition, no stimulation was delivered during the foreperiod. Within each block, TMS was delivered once at each of the ve stimulation times in each of the 12 behavioral conditions, yielding 60 stimulation trials and 36 no-stimulation trials. The trials were presented according to a random sequence generated by the computer. There were three sessions, one training and two experimental sessions, each performed on a dierent day. During each session, the subject successively performed 10 blocks of trials, with a few mn of rest between each block. During the training session, no TMS was delivered and the RT data recorded during this session were discarded. The two experimental sessions diered by the hemisphere ipsi vs. contalateral to the dominant hand ; which was stimulated. The order according to which the hemispheres were stimulated was balanced across subjects. 2.8. Signal processing Some examples of the muscle potential MEP ; evoked by a single presentation of TMS are presented in Fig. 1. Each panel in the gures shows EMG recorded in each.
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Glycemic control since so many things can affect fasting, and the mostly single-digit percentage declines Conjuchem reported could well have been a result of a number of things beyond the drug itself. The side effect profile showed about 20% nausea and higher vomiting in the highest-dose group 3 mg ; . We would think that vomiting is a huge detractor without weight loss as a tradeoff. Management spoke only of severe hypo rates none ; but didn't mention mild to moderate hypoglycemia, so we wouldn't be surprised if there had been some. Lastly, the company didn't say how many patients got to goal, explaining that it hasn't done this analysis yet, which was surprising to us since it seems a pretty straightforward. Management said that it will be pressing on with the phase 2 study, which will be a metformin add-on trial, testing 2-3 doses, 30 patients per cohort, in a 3month study. Merck--EU approval for sitagliptin granted: Sitagliptin was approved brand name Januvia in some venues, Xelevia in others ; in the EU on March 26. The label sounds similar to that in the US, with assessment of renal function recommended at initiation and periodically no requirements ; . Merck apparently only filed for add-on to metformin and or TZD, not add-on to sulfonylurea, which is interesting because the company is pursuing the latter indication in the US now. We note that TZDs are used far more rarely in Europe than in the US, but metformin prescriptions are very common. We understand that tolerability issues aside, the cost of TZDs is a major barrier to getting the drug covered, so it will be interesting to see how sitagliptin does in comparison. We note that Merck made a major push at Diabetes UK on incretins, though they have not yet been approved. Sanofi--FDA panel meeting set for June 13 for rimonabant: Sanofi announced on March 26 that the FDA's endocrinologic and metabolic drugs' advisory committee will be meeting on June 13 to discuss rimonabant's safety and efficacy in preparation for the July decision. We think this will be an incredibly interesting meeting, and this is an excellent example of a meeting that should happen there should be a meeting with obesity specialists, endocrinologists, psychiatrists, psychologists, etc. to discuss this drug that clearly has some real positives for some patients and clearly has some big questions associated with the side effect profile. The decision will come on the heels of the announcement that committees can't include any doctors who have received more than $50, 000 from the company being evaluated. While it might sound like a positive doctors will be able to deliver more unbiased feedback we believe the rule is an unqualified negative because of the risk that panel members will not be as knowledgeable. In our view, the doctors who are compensated by the company for clinical trials, etc., are the ones most likely to understand the products. DiObex--Good phase 2a results for oral anti-cortisol type 2 drug: DiObex announced positive results on March 26 from phase 2a studies with DIO-902, its oral once-daily drug candidate for type 2 diabetes. DIO-902 inhibits synthesis of the stress hormone cortisol. Data from various epidemiological and clinical studies have suggested that a link exists between high cortisol levels and adiposity, insulin resistance, and hyperglycemia--some of the common elements of the metabolic syndrome and type 2 diabetes. The two-week trial with DIO-902 included patients with type 2 diabetes who were randomized to placebo or three different doses of the drug. Patients who received DIO-902 had drops in total and LDL cholesterol as well as modest drops in A1c from fairly low mean baselines values, generally between 7% and 9%. Few side effects were observed per se, but there is a potential for drug-drug interactions because DIO-902 is a purified enantiomer of racemic ketoconazole2, a drug used to treat fungal infections, which does have drug-drug interactions with a subset of statins and a number of other marketed drugs. We understand that DIO-902 is supposed to be cleaner than ketoconazole, but much work in the area needs to be done. Daniel Green, President of DiObex, told us that he expects if everything goes well, the drug could enter phase 3 by early 2009.
Examination means a physical examination and or a procedure to take a sample from the horse for the purpose of testing for a prohibited substance and may include physical examination, urine tests, blood tests and or any other test or procedure at the discretion of the appointed veterinarian and which is necessary to enforce these rules. Examination other than the collection of urine samples may only be by a licensed veterinarian. A rider and or responsible member must submit their horse for examination at the request of the Chief Steward, Head Veterinarian or Drug Steward. For the purposes of these rules, examination may include any or all horses in a single division or in all divisions, any horse entered or any horse withdrawn or vetted-out. Every horse selected for examination: a ; is required to be identified immediately prior to the examination using the identification page of its AERA Horse Logbook; b ; must be left in the control of the examining personnel until the examining veterinarian or the Drug Steward releases the horse; and c ; must be accompanied at all times by the rider and or responsible member.
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