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CBLI received a contract from the DoD's Defense Threat Reduction Agency to develop radiation countermeasure compound Protectan CBLB502. The contract, which CBLI expects to be worth $1.3-$2.4 million, will fund preclinical testing in collaboration with the Armed Forces Rabiobiology Research Institute. CBLI will perform rodent studies and AFRRI will conduct non-human primate testing. Protectan has completed a pilot study as a radioprotectant in non-human primates and is being developed under the FDA Animal Rule, under which marketing approval can be granted based on efficacy in relevant animal models and an acceptable safety risk profile in humans. CBLI plans to submit an IND for a Phase I trial of the flagellin derivative this year. Eli Lilly and Co. LLY ; , Indianapolis, Ind. Business: Infectious LLY will invest an additional $50 million in an initiative focused on multi-drug resistant tuberculosis MDR-TB ; , bringing the pharma company's total contribution to $120 million since 2003. The Lilly MDR-TB Partnership is an alliance of 14 public and private organizations that seeks to improve treatment in countries with high rates of MDRTB. Participants include Partners in Health; the International Council of Nurses; International Federation of the Red Cross & Red Crescent Societies; International Hospital Federation; Purdue University; TB Alert; CDC; World Economic Forum; WHO Stop TB Partnership; and World Medical Association. Human Genome Sciences Inc. HGSI ; , Rockville, Md. MedImmune Inc. MEDI ; , Gaithersburg, Md. Business: Biomanufacturing MEDI will lease a portion of an HGSI facility in Rockville, Md. MEDI plans to use the space to develop and manufacture clinical trial batches of a cell culture-based influenza vaccine. Financial terms were not disclosed. The facility will support MEDI's $169.5 million contract from U.S. Department of Health and Human Services to develop a cell-based pandemic influenza vaccine. The vaccine is expected to enter clinical testing in mid-2008 see BioCentury, May 8, 2006 ; . InterMune Inc. ITMN ; , Brisbane, Calif. Business: Pulmonary, Infectious, Hepatic ITMN plans to reduce headcount by 50% to 115 this year, with the cuts primarily in the clinical, regulatory, medical affairs and commercial areas. The announcement came after ITMN said it would discontinue development of Actimmune for idiopathic pulmonary fibrosis IPF ; after data from a Phase III trial showed the interferon IFN ; gamma-1b did not significantly improve overall survival vs. placebo see BioCentury, March 12 ; . The company hopes the restructuring will reduce annual operating expenses by $40-$50 million starting in 2008. ITMN also withdrew its 2007 revenue guidance of $70-$90 million, citing an expected "significant decline" in off-label sales of Actimmune for IPF. The drug is marketed to treat chronic granulomatous disease and severe, malignant osteopetrosis. ITMN expects to have $205-$210 million in cash at March 31. At Dec. 31, 2006, ITMN had $214.5 million in cash and a full year operating loss of $110.2 million. Neose Technologies Inc. NTEC ; , Horsham, Penn. Business: Hematology, Biomanufacturing NTEC will restructure and reduce its headcount by about 38% to 30 from 50 over the next few months. The company hopes the move will offset increased R&D costs resulting from the recently started Phase II trial of GlycoPEG-EPO NE-180 ; to treat anemia in cancer, for example, lisinopril.
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The pharmac y where you wor k has advertised in the press that they provi de immunisati on ser vices. Subs equent to the appearance of the advert you rec ei ve the following queries from members of the public. Give appropriate res ponses to queries i ; to i bel ow. i ; How s oon after the H epatitis B vaccine woul d the recipi ent be protected against H epatitis B infecti on?. Middot; monoket is in the fda pregnancy category this means that it is not known whether it will harm an unborn baby. Hy did you join the Army? The main reason was to become a medic. I joined the Marine Corps as an Infantryman in July of 1991 just out of high school and did that for four years. While I was in Okinawa I was involved in a Super-Squad competition. I had been training for about eight months, and in the first 15 minutes of the competition I dislocated my elbow and messed up my ankle. While I was on the obstacle course, I jumped up and tried to grab a bar and missed. I came down with my arm out to break my fall and pop! My unit sent me over to the battalion aid station for help and I liked it. Then I went into the Naval Reserves for two years to try and become a corpsman so I could go back and work with. Reducing Health Disparities Among Minority Youth "I attended our local festivities to honor Martin Luther King.A 7th grade African-American student got up in front of everyone and spoke. She told of going through the TNT program at her school and that through this program she learned that she does have a voice. In front of over 200 people she vowed never to use tobacco or any other drug. She then publicly thanked me for teaching all the 7th graders about the dangers of tobacco. Needless to say I was in tears." TTPI Community Schools grantee 274 25% ; of community school grantee activities 133 37% ; priority population activities El Pueblo: Spanish curriculum on tobacco; leadership development among Latino youth, media and community events NC Commission on Indian Affairs: Tobacco-free tribal policies, churches, family evenings General Baptist State Convention: Picture Me Tobacco Free Photovoice project and exhibits, Youth action teams Old North State Medical Society: Physician training for cessation, New youth group formation Provide Treatment Options for Youth Wanting to Quit "In January, I hosted a speaker. At a middle school, after he was done, a student approached us and asked for help quitting tobacco. This almost made me cry because this was a 6th grader and he was reaching out for help.The change starts with just one. The side effects of chemotherapy depend on the type of drugs, the amount taken, and the length of treatment. Temporary side effects might include nausea and vomiting, loss of appetite, loss of hair, and mouth sores. Because chemotherapy can damage the bloodproducing cells of the bone marrow, patients may have low blood cell counts. This can result in an increased chance of infection due to a shortage of white blood cells ; , excessive bleeding or bruising after minor cuts or injuries due to a shortage of blood platelets ; , and fatigue due to low red blood cell counts ; . Most side effects disappear once treatment is stopped. There are remedies for many of the temporary side effects of chemotherapy. For example, antiemetic drugs can be given to prevent or reduce nausea and vomiting, for example, synthroid.

Haajar salah el dean bmj , 10 sep 2006 greatest medical breakthrough since 1840 prerna a sinha, et al bmj , 10 sep 2006 germ theory harvey marrable bmj , 10 sep 2006 anaesthesia gabriel v jaffe bmj , 10 sep 2006 lewis thomas david stevens bmj , 10 sep 2006 greastest medical breakthrough phillip simons bmj , 10 sep 2006 the greatest medical breakthrough enrique snchez-delgado, md, professor bmj , 10 sep 2006 plastic phillip colquitt bmj , 10 sep 2006 the defibrillator must have a place in the list tom quinn bmj , 10 sep 2006 pain, suffering, dignity, and the human spirit.