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Analysis of flock immunocompetence routinely requires determination of titers to multiple pathogens. An assay has been established to simultaneously determine serum antibody titers against multiple pathogens in a single tube in less than 1 hour. Titers for Infectious Bronchitis ark ; , Infectious Bursal Disease Virus, Reovirus, and Newcastle Disease Virus were determined simultaneously from the sera of immunized broiler breeders. Assays were established on the Luminex Multi-Analyte Platform. Immunizing agents were coupled covalently onto individually addressable sets of polystyrene microspheres. Once coupled with antigen, these microsphere sets can be combined to allow the simultaneous quantitation of antibodies specific for each specific antigen. Serum samples are added to the microsphere mixture, and antigen-specific antibodies bind to their respective microsphere set. Nonspecific antibody is washed from the mixture, and microsphere-bound antibody is detected subsequently with a fluorescently labeled anti-chicken IgG. The amount of microsphere-associated fluorescence is quantitated by a flow microfluorimeter equipped with Luminex software. The amount of antigen-specific IgG present in a serum sample is directly proportional to the microsphereassociated fluorescence. Since the flow microfluorimeter can analyze thousands of particles per second, a very large sample size can be generated for each analyte in only a few seconds. Simultaneous analysis of the antibody titer for all 4 pathogens on over 150 different serum samples strongly correlated with previously generated ELISA results. These data indicate that this method is a viable alternative to using multiple ELISA assays for serum titer determinations. The ability to simultaneously perform multiple analyses for different analytes in the same tube greatly reduces assay time, man-hours of work per assay, reagent and consumable usage, as well as serum volume requirements. This assay format allows the simultaneous analysis of antibody titers for as many as 100 distinct pathogens, including strain variants. Key Words: serum antibody titers, infectious pathogens, multiplexed analysis.

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Their main areas of application are nuclear medical examinations such as positron emission tomography pet ; or single photon emission computed tomography spect.
Differences between treatment arms Staring: 38, 40; no significant differences between treatment arms The authors also presented incidence data of side effects reported by teachers as well as mean severity ratings reported by both parents and teachers. Authors' Conclusions: Parent ratings indicated that decreased appetite, insomnia, stomachaches and headaches increased significantly in frequency and severity during the two active medication doses compared with placebo. Stimulant medications, when given in therapeutic doses, are generally safe and produce only minor degrees of side effects in most children with ADHD. Reviewer's Comments: No comments noted and lorazepam. E-COMMERCE E-commerce is rapidly changing the way that the chemical industry conducts business. BASF is taking advantage of the opportunities oered by electronic commerce to improve customer relationships, to enhance its supply chain productivity and to increase its purchasing eciencies. BASF expects to conduct about 40 percent of its business online by the end of 2001, and this level is expected to rise to more than 50 percent by 2005. BASF wants to secure a European leadership position in e-commerce, and plans to invest about 475 million during the next two years to expand its activities. BASF's e-commerce strategy is focused on three major areas: , System-to-system solutions: System-to-system solutions refers to the direct link between the information technology IT ; systems of companies or business partners. This category will continue to account for the majority of electronic marketing activities in the coming years. An example of this is vendormanaged inventory, which is an electronic-based supplier concept that is individually tailored to the customer's needs. It allows BASF to monitor the customer's inventory level and a new order is automatically placed when the inventory level of the product drops below a prespecied amount. This eliminates the need for time-consuming routine purchase orders and allows BASF to ensure that the customer always has an adequate supply of BASF products without any additional action having been taken by the customer. , Electronic marketplaces: In addition to participating in external marketplaces, BASF is building its own specic procurement marketplaces. Some examples of electronic marketplaces in which BASF has an interest include its venture with other chemical companies to launch a marketplace for transactions, logistics and supply chain management; its equity stake in ChemConnect of the United States and its joint venture with various German chemical companies and SAP AG of Germany. , Extranet: The third category involves BASF selling products and services online through its own Extranet or similar portals. Strategic partnerships will play an important role in BASF's e-commerce strategy. The following is a list of BASF principal partnerships in the area of e-commerce: , Project Newco BASF is one of 12 companies that announced in May 2000 that they agreed in principle to create a new, independent business-to-business e-commerce company that will oer integrated solutions and services for buying and selling basic, intermediate, specialty and ne chemicals. The focus of this venture is to remove costs from the supply chain, beneting both buyers and sellers, by developing a marketplace for contract and negotiated transactions, logistics and supply chain management of chemicals worldwide. The new marketplace is expected to enable deep connectivity between the dierent Enterprise Resource Planning ERP ; systems of suppliers and buyers. The company, which is expected to be established in July 2000 and have operational business services in place by the end of 2000, will be an independent entity with its own management team and a board of directors. Its initial capitalization plan will be more than $150 million. The companies participating in the venture include ATOFINA, Bayer AG, BP Amoco, The Dow Chemical Company, E.I. du Pont de Nemours, Mitsui Chemicals Corporation, Mitsubishi Chemicals Corporation, Rhodia S.A., Rohm and Haas Company, Sumitomo Chemical Corporation and Van Waters & Rogers Inc. 84.

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INSULIN If not listed in Chapter 10, all other forms of insulin are Not Covered ; INTAL INHALER INTRON A INVEGA INVIRASE IODOFLEX PAD IODOSORB GEL IOPIDINE IPLEX ipratropium bromide nasal spray ATROVENT EQUIV ; ipratropium nebulizer solution IRESSA isometheptene acetaminophen dichlo MIDRIN EQUIV ; isoniazid ISOPTO CARBOCHOL ISOPTO HOMATROPINE 2%, 5% isosorbide dinitrate isosorbide mononitrate isosorbide mononitrate er itraconazole SPORANOX EQUIV ; JANUMET JANUVIA jolessa SEASONALE equiv ; 3 Copays per Rx ; jolivette ORTHO MICRONOR NOR-QD equiv ; junel fe ; 1.5 30, 1 LOESTRIN FE ; equiv ; KADIAN KALETRA kariva MIRCETTE equiv ; KEPPRA KERALAC LOTION KETEK ketoconazole NIZORAL EQUIV ; ketoconazole cr NIZORAL CR EQUIV ; ketoconazole shampoo NIZORAL SHAMPOO EQUIV ; KETO-DIASTIX ketoprofen ketoprofen er ketorolac 5 Days of Treatment ; KETOSTIX KINERET K-LYTE K-PHOS KYTRIL Retail 9 tabs Rx; Mail Order 27 tabs Rx ; labetalol NORMODYNE EQUIV ; LAC-HYDRIN CREAM LACRISERT lactulose LAMICTAL LAMICTAL CHEW TAB LAMISIL lamotrigine chew tab LAMICTAL CHEW TAB equiv ; LAMPRENE lancets LANOXIN LANTUS.

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This report is subject to the limitations and qualifications set out in Section 5 of this report and in particular, the limited sources of information described in Section 5.1 in this report. 2. PATENTS GENERALLY A patent is a statutory monopoly granted in respect of an invention which in Australia at least, provides the patentee with the exclusive right to "exploit" the invention including the exclusive right to make, use, or sell the patented invention, and to import or export products covered by the patent. This does not mean that exploitation of the invention will not infringe a third party patent. We have not in this report advised on inventorship, or on the existence of, or any possible infringement of, others' patent rights. The grant of a patent does not provide any rights outside of the jurisdiction in which the patent was granted. In most jurisdictions, a patent has a term of 20 years from the filing date of the patent application on which the patent was granted. The patent laws of at least some jurisdictions including those of Australia have provisions which allow for the term of a patent granted in respect of a pharmaceutical substance to be extended, usually by up to years. If it is desired to pursue patent protection in a significant number of foreign jurisdictions, a single international patent application can be filed under the Patent Cooperation Treaty PCT ; designating foreign jurisdictions of interest which are party to the PCT. In order to pursue patent coverage in jurisdictions that are not party to the PCT, it is necessary to file separate patent applications in those jurisdictions. There is no such thing as a world patent, and an international PCT ; application must ultimately be entered into each jurisdiction originally designated in the PCT application and which remains of interest. This is known as entry into the "national phase" or in the case of Europe, the "regional phase". Entry of the international PCT ; application into the jurisdictions of interest effectively converts the application into a bundle of national and or regional patent applications. Each such application is then pursued before the national regional patent office of the relevant jurisdiction. Most national regional patent offices around the world including the European Patent Office, IP Australia and the United States Patent & Trademark Office USPTO ; , conduct substantive examination on a complete patent application. All issues that may be raised by. LEVSINEX . LEVULAN . LEXAPRO . LEXIVA . LEXXEL . lidocaine viscous . lidocaine prilocaine . LIDODERM . lindane . LIPITOR . lisinopril . lisinopril hydrochlorothiazide . lithium carbonate . lithium carbonate ext-rel LITHOBID . LIVOSTIN . OVRAL . LOCOID . LODINE . LODINE XL LODOSYN . LOESTIN FE LOESTRIN . LOMOTIL . loperamide . LOPID . LOPRESSOR HCT . LOPROX . LORABID . lorazepam . LORCET 10 650 . LORCET PLUS and macrobid. Catastrophic health care events: implications for pricing i would view these as different approaches to similar problems, although i must say, without being sycophantic, that i was truly impressed with what dave was doing yesterday, because 24 loestrin missed period.

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Right to Health & Essential Drugs List The right to health has been recognized in Ghana's Constitution since Article 24 was implemented in 1992. Access to treatment is not stated categorically but is implied. Ghana's Essential Drug's List does not cover HIV AIDS treatment. Access to Treatment The public health sector provides treatment to less than 1% of PLWAs, through a pilot project. To qualify for these social and public insurance benefits, an individual must contribute to the scheme. The treatment available includes: treatment for STDs; treatment for opportunistic infections, including TB; mono therapy; double bi therapy; triple therapy; protease inhibitors; palliative care; and, nutritional supplements. Other than through this pilot, ARVs are not available at government public health institutions. In the past five years, there have been specific programs to benefit all members of society, including STD treatment for sex workers. There have been improvements in access to treatment. However, even though ARVs are now available at pharmacies ; , the high cost of these drugs puts them beyond the reach of most patients. The majority of PLWAs make their own arrangements for treatment. Most PLWAs depend on traditional herbal medicine, most of which is not tested for efficacy and safety. The private sector does not cover treatment for HIV AIDS. Government & Pharmaceuticals The government of Ghana is not in negotiations with pharmaceutical companies to lower the prices and make ARVs more available to the population. Community Participation The Ghana HIV AIDS Network has interacted with the government to improve access to treatment through lobbying and meetings with government authorities. It also advocates for pharmaceutical companies to allow parallel imports through press publications and email campaigns. Prolink interacts with the government to increase access to treatment through lobbying the government and meeting with officials. International Guidelines The Ghana HIV AIDS Network was aware of the International Guidelines through UNAIDS publications but has not yet applied them to advocacy work. Prolink was unaware of the International Guidelines and has not incorporated them into advocacy efforts. There have been several positive changes in government policies in the last five years to structure a more comprehensive national response to HIV AIDS. In 1999, the government issued a communiqu after the International Partnership against AIDS in Africa consultation to establish a program for social mobilization against AIDS. A supra-ministerial and multi-sector body involving all government ministries, the private and medroxyprogesterone. REVIEW AND ADOPT MINUTES FROM APRIL 20, 2004 Mr. Arteaga moved to adopt the minutes from April 20, 2004. Mr. Wellington seconded the motion. The motion carries. INITIATIVE UPDATES 1 ; Pharmacy Update by Deloitte ; Ms. Menge referred the Board members to the "Pharmacy" tab in their packets. Mr. Pechacek and Mr. Kurtzweil from Deloitte introduced themselves. Mr. Pechacek noted that Deloitte was asked to review two prescription drug options for the retiree medical plan: Dispensed as written DAW ; options and over-the-counter OTC ; prescriptions. He explained that in general, DAW pertains to a prescription being filled with a brand drug even though a generic drug was a therapeutically equivalent option. There are two main kinds of DAW options: DAW 1, where the physician requests that a brand drug be used, and DAW 2, where the patient requests that a brand drug be used but is not required by the physician. Mr. Pechacek explained that Aetna has proposed that the State consider placing restrictions on the use of DAW orders in which the DAW procedures would be restricted, and also the member would pay the difference between the brand and the available generic copayment if DAW was included in the prescription. Aetna proposes that if there was a generic available, the member would have to pay the added cost to the Plan for choosing a brand drug. Responding to Mr. Wellington, Mr. Pachacek explained that under the DAW 1 option, if the physicians were required to prescribe generic drugs, there would be an average cost savings of $50 per script written. For the 22, 389 scripts written in 2003, the State could have potentially saved $1, 122, 137. Under the DAW 2 option, if the patient were required to select a generic drug if prescribed, for the 33, 565 scripts written in 2003, the State could have potentially saved $1, 672, 254. The potential savings to the State in 2003 for both DAW 1 and DAW 2 options would have been $2, 794, 391. Mr. Wellington stated he was not comfortable with requiring a physician to prescribe a generic drug under the DAW 1 option. Chair Harbo agreed. Mr. Pechacek stated that under DAW 1, the physician would have to be contacted to determine if the brand drug was indeed medically, for example, 120 fe loestrin. Fioricet, Fioricet W Codeine Fiorinal, Fiorinal W Codeine First-Progesterone MC VGS Flagyl ER Flexeril Flextra DS Flonase Florinef Florone Floxin Oral Flumist FML Liquifilm Focalin XR Fortamet Freestyle Frova Gabarone Gabitril Geocillin Geodon Glucometer Dex Elite Encore Glucophage XR Glucotrol XL Glucovance Glynase PresTab Glyset Golytely Grifulvin V Susp. 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The following is the summarized financial information for versicor and hemasure: enlarge download table 1998 1997 in thousands ; versicor hemasure versicor hemasure - current assets $ 9, 631 $ 3, 383 $19, 610 $ 9, 097 non-current assets 6, 454 2, current liabilities 2, 293 3, non-current liabilities 6, 034 5, net sales - 25 - 2, 357 gross profit loss ; - 632 ; - 1, 801 ; net income loss ; $ 11, 280 ; $ 12, 170 ; $ 6, 203 ; $ 9, 884 ; e - investments investments consist of the following at december 31: enlarge download table in thousands ; 1998 1997 - cash & cash equivalents: cash & money market funds $ 14, 279 $21, 568 corporate & government commercial paper 281, 044 61, - total cash & cash equivalents $295, 323 $82, 579 marketable securities: government securities due within 1 year $108, 239 - corporate commercial paper due within 1 year 86, 035 9, due within 1 to 2 years 10, 000 total investments $204, 274 $9, 981 there were no gross realized gains or losses on the sale of marketable securities for the years ended december 1998, 1997 and 199 thirty-seven ex-13 40th page of 47 toc 1st previous next bottom just 40th notes to consolidated financial statements continued ; f - financial instruments financial instruments consist of the following at december 31: download table 1998 carrying fair in thousands ; amount value - convertible subordinated debentures - 6-1 4%, due 2005 $189, 475 $368, 766 convertible subordinated debentures - 7%, due 2005 $300, 000 $300, 000 the fair value of the 6-1 4% debentures due 2005 is from a quoted market source and methylprednisolone. In case of severe extrapyramidal reactions, antiparkinsonian medication should be administered.
Like medicine, genetic research begins with people see figure ; . In the case of dystonia research, it begins with people with any type of dystonia or a related movement disorder. When a doctor sees many people who have the same health problems and other characteristics especially if the people are family members ; , the doctor begins to ask questions about the condition and begins to wonder if something genetic is causing the similar health problems.

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Iii ; Propagation. To maintain continuous thrombin generation, ensuring the formation of a sufficiently large clot, large amounts of FXa are produced by the activation of FX by FIXa and FVIIIa intrinsic tenase complex ; . FIXa stems primarily from the activation of FIX by the FVIIa TFcomplex. iv ; Stabilization. Maximum thrombin generation occurs after the formation of fibrin monomers. Only then is the amount of thrombin high enough to activate FXIII, a transglutaminase, which then cross-links the soluble fibrin monomers to a stable fibrin meshwork. In addition, thrombin then activates the TAFI ; that protects the clot from fibrinolytic attack. Surgical procedures often unbalance this elaborate system, leading to a tendency to either thrombosis or bleeding. Besides the operative intervention itself and many wellknown clinical risk factors, including immobility, infections, cancer and drugs, there are various other perioperative factors that are increasingly being demonstrated to interfere with the coagulation system, such as hypothermia, 56 metabolic acidosis, 26 volume expanders49 and extracorporeal circulation.8 Such perturbation of coagulation can be assessed by various laboratory assays. For example, during the first several hours after surgery there are marked increases in tissue factor, tissue plasminogen activator, plasminogen activator inhibitor-1 PAI-1 ; and vWF, leading to a hypercoagulable and hypofibrinolytic state, as evidenced by increased generation of coagulation activation markers, such as thrombinantithrombin complexes, fibrinopeptide A and many others.52 57 The levels of these mediators are known to fluctuate rapidly and their degree of perturbation is dependent not only on the type.

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