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CENTER FOR MIND-BODY MEDICINE COMPREHENSIVE CANCER CARE 2001 PLENARY SESSION : CAN LIFESTYLE CHANGES AFFECT THE PROGRESSION OF PROSTATE CANCER? SPEAKER: Dean Ornish, MD Arlington, Virginia Sunday, October 21, 2001 PROCEEDINGS DR. BROWN: Our final plenary speaker is Dr. Dean Ornish. And in many ways it's very appropriate that Dean is the -- is the clean-up hitter, as it were, on this program. Both Michael Lerner and Bill Fair have talked about their personal connection to Dean and the deep respect in which they hold his work, and -- and I feel very much the same way. I feel especially increasingly with our work together on the White House Commission, very much a sense of a comrade. And I've also felt, ever since I first met Dean, which is probably about 25 years ago now, that this was someone with both a true vision and a passion to make real so many of the principals and practices that were important to me 25 years ago, that are important to all of us today. Dean is both a wonderful scientist, and I mean that, wonderful, with all the sense of that word, he's a scientist who is full of wonder, and he's wonderful at doing the scientific work, and at the same time he is a -- visionary, and at the same time he is, in the deepest sense of the world, a true revolutionary, because what his work has done and is doing and is showing now to increasing numbers of people is that it is possible for quite ordinary people to learn how to do relatively simple things, to learn how to use easily available tools, and to profoundly change and extend their lives, and to transform their whole outlook on the world. And the implication of this, the implication of Dean's work, and I almost always quote his work because I think it's the single best example we now have, is that we are entering a new era of true healing partnership between those of us who are professionals and those of us who are patients and between that side of ourself that is professional and that side of ourself that is always a patient and wanting to do better and care for ourselves better. The work he's done with heart disease, Michael's suggestion is not hyperbole at all, it is the kind of work that is certainly deserving of a Nobel prize. I think it may well be the most important medical and health work that's going on now. Dean has now, in recent years, begun to look at the applicability of this truly integrative approach, this approach that's truly grounded in self-care and self- awareness and wellness that is a sustainable and an economically sustainable approach. He's begun to turn his attention to prostate cancer from his groundbreaking work with heart disease. And so it was with great pleasure that -- that I invited Dean, and even greater pleasure that I welcome him here today to share with us his vision and his work. DR. ORNISH: Thank you for that kind introduction. I feel like I should quit while I'm ahead and say thanks, bye. I really feel honored to be here with Jim, with Bill, with Michael, three people who I love and respect more than just about anybody in this field, and the work that Jim is doing with the White House Commission, but even more so, I think the work he's been doing in Kosovo the work that Bill Fair has done was a direct -- he's collaborating with me on the prostate study, but his work really inspired the prostate study, which I'll talk about, and Michael, who's been a dear friend for many, many years. I have to say that was if not the best lecture I've ever heard, certainly one of the top two or three best lectures I've ever heard in my entire life, and certainly the most inspiring, and so I and
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Paper Presenter: Donald West, MD, Dartmouth Medical School Dartmouth-Hitchcock Medical Center, Lebanon, NH Co-Authors: Rebecca Hirsch MD, Lorna Mayo MD, Duke Fisher MD, Deena Morey, BA Date: Sunday, December 12 Time: 9: 20-9: 40 a.m. Location: Gardenia 1 The need for treatment for opioid dependent patients as well as the need for developing physicians comfortable with treating such patients presents a significant challenge. This situation is made more complex when it occurs in an institution and a geographic area which had previously had no opioid dependence treatment and no one with experience administering it. The presentation will include discussion of the procedure used for initiating such treatment at Dartmouth Hitchcock Medical Center in Lebanon, NH as heroin OxcyContin were becoming epidemic in Northern New Hampshire and Vermont. It will include discussion on how the program was developed and evolved utilizing weekly medication group counseling sessions run by PGY IV psychiatry trainees under close supervision, with direct clinical involvement by a faculty addiction psychiatrist. It will include data on the patient population, intake and treatment policies, payment issues, drug screening, retention, and patient outcome data from the first year of the program. Discussion will also include the impact the program had on the institution and the gradual development of interest in treating opioid dependent patients as well as involvement of patients from the program in medical student education and
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1. Seeff, L.B. Natural history of hepatitis C. Hepatology 1997; 26 Suppl 1 ; : 21S-28S. 2. Remis, R. A study to characterize the epidemiology of hepatitis C infection in Canada, 2002. Final report. 2004. Ottawa: Health Canada. 3. Zou. S., Forrester, L., Giulivi, A. Hepatitis C update. Canadian Journal of Public Health 2003; 94 2 ; : 127-129. 4. Tortu, S., McMahon, J., Pouget, E., Hamid, R. Sharing of noninjection drug-use implements as a risk factor for hepatitis C. Substance Use & Misuse 2004; 39 2 ; : 211-224. 5. Hagan, H. Hepatitis C virus transmission dynamics in injection drug users. Substance Use & Misuse 1998; 35 5 ; : 1197-1212. 6. Patrick, D.M., Tyndall, M.W., Cornelisse, P.G.A., Li, K., Sherlock, C.H., Rekart, M.L. et al. Incidence of Hepatitis C virus infection among injection drug users during an outbreak of HIV infection. Canadian Medical Association Journal 2001; 165 7 ; : 889-895. 7. Lamothe, F., Vincelette, J., Bruneau, J., et al. Prevalence, seroconversion rates and risk factors for hepatitis B core, hepatitis C and HIV antibodies among intravenous drug users IDU ; of the Saint-Luc Cohort abstract 221 ; . 6th annual Canadian Conference on HIV AIDS Research, May 1997. Canadian Journal of Infectious Diseases 1997; 8 Suppl A ; : 28A. 8. Fischer, B., Rehm, J., Brissette, S., Brochu, S., Bruneau, J., el-Guebaly, N. et al. Illicit opioid use in Canada: Comparing social, health and drug use characteristics of untreated users in five cities OPICAN study ; . Journal of Urban Health. In press. 9. Carlson, R., Wang, J., Siegal, H., Falck, R. A preliminary evaluation of a modified needle-cleaning intervention using bleach among injection drug users. AIDS Education and Prevention 1998; 10 6 ; : 523-532. 10. Jamner, M., Corby, N., Wolitski, R. Bleaching injection equipment: influencing factors among IDUs who share. Substance Use & Misuse 1996; 31 14 ; : 1973-1993. 11. Vlahov, D., Junge, B. The role of needle exchange programs in HIV prevention. Public Health Reports 1998; 113 Supplement 1 ; . 12. Marsch, L. The efficacy of methadone maintenance interventions in reducing opiate use, HIV risk behavior and criminality: a meta-analysis. Addiction 1998; 93 4 ; : 515-532. 13. Fischer, B., Remis, R., Haydon, E. Hepatitis C, illegale Drogen und marginalisierte Populationen in Kanada: Ein kurzer Uberblick zu Epidemiologie, Pravention und Behandlung. In: Stover Heal, Ed. ; Tagungsband zum 1. Internationalen Fachtag zu Hepatitis C. Berlin: 2004. 14. Fischer, B., Rehm, J., Kim, G., Robins, A. Safer Injection Facilities SIFs ; for Injection Drug Users IDUs ; in Canada: A review and call for an evidence-focused pilot trial. Canadian Journal of Public Health 2002; 93 5 ; : 336338. 15. Kapadia, R., Vlahov, D., Des Jarlais, D., Strathdee, S.A., Ouellet, L., Kerndt, P. et al. Does bleach disinfection of syringes protect against hepatitis C infection among young adult injection drug users? Epidemiology 2002; 13 6 ; : 738-741.
Address reprint requests to melody ryan, phar , university of kentucky medical center, 800 rose street, c117, lexington, ky 40536-008 department of neurology, college of medicine, university of kentucky; and the department of veterans affairs, lexington, kentucky and
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8. Ranolazine Renal Impairment Alert Message: The use of Ranexa ranolazine ; should be avoided in patients with severe renal impairment. In six subjects with severe renal impairment receiving ranolazine 500 mg b.i.d. the mean diastolic blood pressure was increased approximately 10 to 15 mmHg. If ranolazine therapy is necessary monitor blood pressure regularly. Conflict Code: MC Drug Actual ; Disease Precaution Drugs Disease Util A Util B Util C Ranolazine Renal Impairment References: Ranexa Prescribing Information, Feb. 2006, CV Therapeutics, Inc and
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The use of PharmaNet is not intended as a substitute for professional judgment. Information on PharmaNet is not exhaustive and cannot be relied upon as complete. The absence of a warning about a drug or drug combination is not an indication that the drug or drug combination is safe, appropriate or effective in any given patient. Health care professionals should confirm information obtained from PharmaNet, and ensure no additional relevant information exists, before making patient care decisions and clonazepam and carisoprodol, for instance, carisoprodol pregnancy.
The laws in Ohio and State Board of Pharmacy rules are such that they encourage the substitution of generically equivalent drugs. The rules provide the pharmacist with guidelines to enable him or her to substitute in order: 1. To pass on cost savings to the public. 2. To maintain a profitable gross margin equal to that if substitution was not chosen. 3. To not incur additional liability if one chooses to substitute. 4. To assure that the patient is always informed that substitution of a generically equivalent drug has taken place, and that he or she always retains the right to reject substitution. The pharmacist is required to assess the generic equivalency of the products chosen to be substituted for others. The reliance on an "A" rating in the Orange Book is not absolute. The working definition of generic equivalency can be found in ORC 3715.01 A ; 16 ; . The pharmacist is free to substitute on grandfathered drugs manufactured prior to1938 ; , DESI.
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