Accession number & update 16939933 Medline 20070116. Source Drug and alcohol review Sep 2006, vol. 25, no. 5, p. 393-402, ISSN: 0959-5236. Author s ; Schuckit-Marc-A, Smith-Tom-L. Author affiliation Department of Psychiatry, University of California, San Diego and the VA San Diego Healthcare System, San Diego, California 92161-2002, USA. mshuckit ucsd . Abstract Externalising behaviours, including the personality characteristics of behavioural undercontrol BU ; , represent one of several genetically influenced domains that impact on the alcoholism risk. Because genes explain only about 60% of the vulnerability toward alcohol use disorders AUDs ; , an optimal understanding of how such behaviours affect the risk requires evaluation of their impact in the context of additional influences. Few studies have addressed this question regarding BU among relatively well-functioning adults. This paper presents results from testing a BU-based mediational model of risk in men from the San Diego Prospective Study. Structured research instruments were used with 430 adult Caucasian males to evaluate the performance of BU in predicting AUDs at the 15-year follow-up using Pearson product - moment correlations among domains and an AMOS-based structural equation model SEM ; . While both the family history of AUDs FHalc ; and BU predicted alcohol-related outcome, BU by itself did not mediate the relationship of the FH to alcohol disorders. The impact of BU on alcohol problems was mediated by alcohol expectancies, peer drinking and by coping. The SEM explained 42% of the variance for AUDs. The current results indicate that BU contributed to the risk for alcohol-related problems, even among more highly functional subjects and after excluding the impact of the antisocial personality disorder, but by itself did not mediate the relationship of FH to outcome in these subjects. Grant ID: 05526, Agency: PHS. Language English. Publication year 2006.
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Mines could impair clearance by thickening mucus.31 Newer second-generation antihistamines have little or no anticholinergic effect and may have a role in treatment of patients with allergy and chronic sinusitis, but are not recommended for ABRS.48 The topical anticholinergic agent ipratropium bromide Atgovent ; has been used to decrease rhinorrhea in patients with the common cold, 32 but there are no studies in patients with ABRS. Theoretically, ipratropium may increase the viscosity of mucus and impair its clearance, but this effect appears to be less prominent with ipratropium than with antihistamines.31 Most studies of intranasal steroids in patients with ABRS have not shown an effect on clinical outcomes. These studies often were underpowered and included patients who had chronic sinusitis and nasal polyposis, as well as ABRS.33-36 A recent RCT, 37 limited to patients with a history of previous recurrent or chronic sinusitis, compared fluticasone Flovent ; with placebo in the treatment of patients with ABRS. Both groups received cefuroxime and topiTABLE 3.
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Played important roles in the planning of key elements of the Institute. Statewide objectives were developed for this Institute and are linked to a follow-up evaluation for the Institute: By the end of 2004, mobilize youth and adult leaders of youth for a focused and highly visible campaign to eliminate secondhand smoke from at least 50 public places where youth frequent, and gain increased earned media at the local level at a rate of 3 media events per month. By the end of 2005, increase from 45 to 75 the number of school districts actively working to advance a 100% tobacco-free school policy. By the end of 2005, increase from 30 to 59 the number of school districts that adopt and enforce a 100% tobacco-free school policy. By mid-2004, increase to at least 20 new communities that are mobilized around the most effective NEW ways to reduce youth access and availability, including educating about the research on public health effectiveness of a price increase. By mid-2004, all adult participants and at least half of all youth participants sign up to be part of the QuitNowNC! Network in order to promote quitting among youth and adults. By the end of 2004, at least 10 communities or schools will plan and implement at least one evidence-based cessation policy program intervention within a school system, healthcare setting, or worksite. A comprehensive evaluation plan was developed for the Youth Leadership Institute. Each individual course was rated by attendees and feedback provided to both the HWTF and to course facilitators. Most courses were given high ratings and participants stated that their learning objectives were met. In addition, a palm pilot survey was developed and administered when the majority of participants convened for dinner one night. Immediate results gave high marks for the overall training, general sessions, whether youth and adults had learned new skills, and whether those new skills would be put into use in their home communities. Between 80-90% of all youth and adults stated that they had learned a new skill that they intended to use it back home and that overall the training met their needs. See Appendix 3. Because less is known about how these skills actually translate back into their community's two specific follow-up surveys were planned. A 3-4 month follow-up survey with all youth and adults using the Internet, mail and telephone was conducted to see how these skills were being utilized. Nearly half of the 450 participants were contacted and completed a simple 20 question follow-up survey. Also, because a specific task at the Institute was to develop an action plan, a 6 month follow-up is being conducted to assess to what extent these plans were developed and implemented by the various local youth teams. The six-month follow-up is currently taking place to contact youth and adult team leaders and the results will not be generated until November December 2004. Because of the methods of this evaluation plan, an abstract for a presentation is being submitted to the National Tobacco Control Conference in Chicago, May 2005 that utilizes this evaluation as a case study for other tobacco control programs to learn and replicate. Tobacco-Free School Campaign. The number of school districts that are 100% tobacco free increased from 27 to 43 since this Project was funded. The HWTF Teen Tobacco Prevention and Cessation program provided momentum and ground troops to the Branch's existing campaign to have all schools in NC 100% tobacco free. The 2004 Tobacco Free schools law also provided momentum G.S. 115C-407 clarifying that the local School Board is the appropriate decision-making body for this decision. Regional Tobacco Free Schools Workshops, Leadership Forums, TobaccoFree School Signage Project and the Tobacco Free Schools website are the engine behind the success. They provide the focus, skills, and positive peer pressure to get the job done. Regional Tobacco-Free School Workshops. The TPCB planned and implemented three 2-day 100% Tobacco Free Schools workshops entitled Teaming Up for Tobacco Free Schools during, for example, atrovent dose.
Steroid fluticasone. The rationale behind combination drugs is to improve compliance, as patients with COPD are often unwilling to use multiple drugs and inhalers to gain better control of their condition. Another combination inhaler is Symbicort, in phase III testing in Europe by AstraZeneca. It contains budesonide Pulmicort ; , a corticosteroid, and formoterol Oxis ; , a long-acting beta-2 agonist bronchodilator. Oxis is also available alone as a dry powder in the Turbuhaler inhalation device. Both products have been widely tested in asthma. As of February 2003, AstraZeneca successfully completed the Mutual Recognition Procedure in the European Union for the treatment of COPD with Oxis Turbuhaler as maintenance therapy, with additional doses as required, up to a maximum total daily dose of 36 micrograms. Bronchodilation with Oxis begins within minutes, as rapidly as with salbutamol, and is sustained for at least 12 hours, as long as with salmeterol. In seven clinical trials involving 2, 416 patients, Oxis was an effective maintenance treatment for COPD, and additional doses could be added as needed for symptom relief. In one study of 657 patients, six months of maintenance therapy with Oxis, 9 micrograms twice daily, led to improved lung function, symptom relief and reduced use of beta-2-agonists for symptom flares. Another formoterol product is R, R ; -formoterol, a single-isomer bronchodilator in phase III development by Sepracor. In phase II testing, once daily inhalation was tolerated as well as other beta-agonists, and it significantly improved FEV1 [forced expiratory volume in 1 second] immediately after dosing, with a duration of action of up to hours. Serevent salmeterol xinafoate ; is a long-acting, orally inhaled beta-2-adrenergic receptor agonist in phase III testing for COPD by GlaxoSmithKline. Its mechanism of action is to increase cyclic AMP via stimulation of adenyl cyclase, which relaxes bronchial muscle and inhibits release of hypersensitivity mediators. Like other beta-2-agonists, Serevent has come under close scrutiny for possibly increasing morbidity and mortality in asthma, but the preponderance of evidence suggests that it is safe as well as effective. An alternate approach to bronchodilation is through localized anticholinergic activity, as is the case with Spiriva tiotropium bromide ; , in phase III testing by Boehringer Ingelheim. Spiriva has been approved by the Medicinal Evaluation Board in Den Haag, Netherlands, for maintenance treatment in COPD. Tiotropium bromide, a new chemical structurally related to ipratropium bromide Qtrovent ; , is a long-acting inhaled antimuscarinic bronchodilator administered once daily with the HandiHaler inhalation device. In a six-month study involving 623 COPD patients, those receiving tiotropium had significantly improved lung function measured by FEV1 compared with patients receiving either placebo or salmeterol. Breathlessness and health-related quality of life were also better than in patients receiving placebo. Tiotropium maintained its effectiveness during the course of the study. The selective phosphodiesterase PDE-4 ; inhibitors are useful in COPD primarily by reducing release of inflammation mediators. Roflumilast, in phase III testing by Altana, is a highly potent and selective orally administered PDE-4 inhibitor. When tested in asthma, its anti-inflammatory actions significantly decreased late responses to allergen, but it did not act as a bronchodilator. Ariflo cilomilast; SB 207499 ; , a phase III product of GlaxoSmithKline, is also an oral.
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Requirement in the state of Minnesota for all mental health providers. All employees and trainees working in the human services and mental health services, should demonstrate mastery and ongoing implementation of cultural and linguistic skills in working with their clients, as evaluated by state established standards. Emphasize culturally and linguistically competent screening, Establish state standards for mastery identification and assessment of cultural and linguistic skills in tools and methods for all children working with persons with mental and families across all "basic illnesses emotional disturbances. spheres of life" -- social, physical, Require state wide training in intellectual, emotional including cultural and linguistic competence chemical health ; and spiritual [Dr. for all administrators and Allden, 1999].11 employees in all state departments, Ensure that all children and counties and private health plans. 10 families from diverse communities Make such training a licensure have access to culturally and.
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An advanced directive is a legal document written in advance of illness that allows you to specify the type of medical treatment you would or would not want. In New Hampshire, we have two kinds of advance directives: the living will and the health care power of attorney. A living will is a statement that says that if you become terminally ill or permanently unconscious, you don't want to be kept alive artificially. If you sign a living will, you are saying "I want be allowed to die naturally, and no life-sustaining treatment should be given to prolong the dying process." Do not sign a living will if you do not agree with this approach to end-of-life care! A health care power of attorney is a document where you appoint someone called your "agent" ; to make medical decisions for you if you are unable to make decisions for yourself. You can choose someone you trust to serve as your power of attorney; someone you would want to make health care decisions on your behalf in the event you cannot. Both of the above documents permit you to specify whether you want artificial feeding or hydration and other types of "life sustaining treatment." Living will and health care power of attorney forms can be obtained from any hospital, as well as from the Foundation for Healthy Communities, your local senior center, or your doctor. It is not necessary to hire a lawyer to help with your living will or health care power of attorney, but you should take care to follow the form's directions carefully. Many senior centers can help with the signing of these documents. Copies of both your living will and health care power of attorney should be given to your agent, local hospital, mental health center, and doctor s ; . Remember! Make your own medical decisions as long as you can communicate with your doctor even if the care you want goes against your advance directives! ; . Only if your doctor decides you are unable to communicate or to make informed medical decision will your agent and advance directives take over. State law says medical treatment cannot be given to you or withheld from you over your objections! Under no circumstances is it legal to withhold food or water if you can eat and drink normally. It is important for older adults to discuss their values, wishes, and worries about end-oflife care with their agent, loved ones, and their health care provider. It is better to let everyone know where you stand on these often emotional issues before you become ill, for instance, atrvoent med.
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CONDITIONS: A. Student will be tested indoors with a mannequin. B. The mannequin will be placed on a tile floor in a cramped room. C. Student will use any one of the IHCC ambulances. D. Student is part of a two person EMT-P crew; E. Student is responsible for the actions of his her assistants. F. Student will work under the medical guidelines of the EMS system where they are completing their internship. G. There are two first responders on scene. H. The patient will not be transported to the mock hospital, the case will stop 5 minutes after the patient has been loaded in the ambulance. STANDARDS: Student is graded on a Pass Fail standard based on demonstrated knowledge, confidence and competence using equipment. Critical Failure Criteria consists of 1 ; exceeding 30 seconds, breath to breath, during any intubation attempt 2 ; using the teeth as a fulcrum 3 ; failure to successfully intubate the mannequin in three attempts at visualization 4 ; failure to confirm placement of ET tube with three or more methods and reconfirm placement after movement 5 ; failure to assemble and begin administration inline nebulizer within 2 minutes of beginning the assembly 6 ; any action which puts crew or patient in danger of injury 7 ; obvious unfamiliarity with equipment 8 ; failure to listen to feedback openly or being disrespectful to the instructor, patient, or crew 9 ; failure to ventilate at an appropriate rate and inspiratory expiratory ratio 10 ; failure to administer albuterol, atrovent and epinephrine 11 ; failing one task listed above and
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In an email alert sent April 4 to more than 32, 000 biomedical researchers, Dr. Hendrix asked her colleagues to contact members of Congress and urge them to increase funding for the National Science Foundation NSF ; . "Once again, Senators Christopher "Kit" Bon R-Mo. ; and Barbara Mikulski D-Md. ; are circulating a `dear colleague' letter to Senate Majority Leader Trent Lott and Democratic Minority Leader Thomas Daschle advocating a doubling of the NSF budget over five years, " Dr. Hendrix wrote. "We must support this effort now!" President Bush has proposed a $4.47 billion budget for the NSF in FY 2002. This request represents a 1.3 percent increase in the foundation's budget; research activities would decline by 0.5 percent. In its annual report to Congress, FASEB recommended the NSF budget for FY 2002 be increased by at least 16 percent, to $5.1 billion ; . That report is online at : faseb opar fund2002 fedfund02 . Dr. Hendrix's testimony to Congress on behalf of the NIH can be found at faseb opar ppp nsf test and
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Interaction with clinical staff in Wellington. It may be that there was locally some agreement either explicit or implied that allowed such registrar communication. 25 ; Systemic issues that have contributed to deficiencies in [Mr A's] care include: a. Staffing. There was a lack of continuity of care amongst junior medical staff and probably a shortage of such. Nursing staff were short and [Mr A] was looked after by an enrolled nurse probably without sufficient senior supervision. b. Lack of High Dependency Care. It may have been available but it was certainly not used. c. Probable lack of availability of chest X-ray at some of [Mr A's] care. I have no information on where and when the films became available. d. The failure of the smoking policy to provide those who crave nicotine some of whom are at the end of their lives ; with appropriate means to relieve their distress. This is an issue throughout the New Zealand health system. e. A culture in which there seems to have been abject failure to consult senior medical staff when appropriate. f. Lack of full consultation with the Coronial Service. In addition to the above, I think comment needs to be made about the respiratory referral. It would not be considered standard practice for a respiratory Registrar, [Dr K], to be consulted by a senior physician, [Dr D], advise over the phone that theophylline would be inappropriate, recommend [an] Agrovent nebuliser and proceed no further. It is standard practice for Registrars when consulted on behalf of their specialist team, to discuss that consultation with their Consultant. In the case of [Mr A], [Dr D] was significantly concerned about [Mr A's] progress. He asked for advice and the Respiratory Team, in particular [Dr K], should have come to see [Mr A]. Once more this was a lost opportunity to review the chest X-ray and reach a rapid diagnosis. This consultation should have occurred on the morning of the 24th of September. It is not clear what support was available to [Dr K] nor what instructions he had been given by his supervising consultant or the Respiratory unit about responding to requests for help. In reviewing the information available to me, I believe that: [Dr D's] clinical care of [Mr A], in particular his failure to ensure that the Xray was reviewed, the blood tests were seen and the significance of the fever was noted and his failure to oversee the total care of [Mr A] including the referral to the Coroner, falls significantly below the standard of care expected of his peers and I believe his peers would view his conduct with moderate disapproval.
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My name is . We are here on behalf of GRPA and MOH to find out what services you have dealing with HIV AIDS. Your facility was chosen tob e a part of this study. We will be asking Your facility was selected to participate in this study. We will be asking you several questions about the types of questions about HIV AIDS care and support services. That is medical, psychological, emotional, and social needs of patients living with HIV AIDS and their families. First, I will read you a statement explaining the survey. Then I will ask for your consent to answer the survey questions. We are interested in care and support that you provide for clients who you either suspect are HIV-infected and those who are confirmed by blood test. We would like to see registers of these patients, but will not be using the information otherwise. Names from the register will not be reviewed, recorded, or shared. Besides the organizations conducting the survey, the information you share about services and systems currently available at your facility will be made available only to program planners at Famiy Health International so they can plan program improvements. You will not be identified by name as giving any particular answers to these questions. Do not worry if you cannot provide all the answers. You can stop the interview at anytime if you do not wish to answer any questions. Hovever, the information you provide is extremely valuble. It will help health facilities improve care and support for HIV AIDS so they can formulate policies and deliver better services, so we hope you will agree to participate. Do you have any questions?.
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