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Gain a woman's consent to a "vaccine" while withholding information about what it is for. Given the fact that vaccines are commonly seen as a very positive form of disease prevention, women are likely to participate willingly in "vaccination campaigns." Yet the term "vaccine" is clearly a misnomer. Vaccines work by stimulating an individual's normal immune system so it can fight off a particular germ more effectively. Fertility and pregnancy, however, are neither illnesses nor diseases. Immunological contraceptives create an immune disturbance which cause the immune system to attack a healthy, normal body process, one which an immune system would normally protect. Under ordinary circumstances, this reaction itself would be considered an illness. Immunological contraceptives are clearly not "vaccines." Immunological contraceptives require a thorough medical examination, documentation of a woman's medical history, and frequent follow-up. Women would need easy and regular access to health services for tests of antibody levels in the blood, for check-ups and for treatment of complications. A very good administrative system would also be necessary to ensure that women are not "lost" to follow-up, and that their experiences with the method can be monitored. These conditions are simply not available to most women in the Third World, the women who are currently the target of test trials and who will, undoubtedly, serve as the primary users. Immunological contraceptives pose hazards and risks to the immune system and threaten to weaken it. A weakened immune system can have devastating effects on women who are already malnourished, or who are at high risk of chronic disease, including malaria, dysentery and tuberculosis. Malaria and tuberculosis epidemics continue to wreak havoc on Third World communities. Because immunological contraceptives are still being developed, we do not know their long-term effects, but all indications are that the risks far outweigh the negligible benefits for women. Research into immunological contraceptives is dangerous and should be stopped immediately. Research must be redirected into safe, user-controlled and effective methods of contraception, for example, alphagan brimonidine.
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In terms of impact on public health and healthcare costs, Alzheimer's and Parkinson's disease contribute the overwhelming bulk of the neurodegenerative disease burden. A correspondingly large amount of research funding is being spent on these disorders. This has not been without some initial success, although we have taken only the fist few steps on a long road which is still before us. Dementia Although dementia has become all but a synonym for neurodegenerative disorder, the term describes a psychiatric syndrome, not a specific disease. Purely vascular dementia can exist without neurodegenera and amaryl.
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Author s ; : gerstein hc, garon j, joyce c, rolfe a, walter cm affiliation s ; : division of endocrinology and metabolism, mcmaster university and hamilton health sciences, 1200 main street west, hamilton, ontario l8n 3z5, canada and
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Design: Mathematical No. of pre-ESRD subjects: NA simulation variable-volume, single-pool, urea kinetic model ; Inclusion criteria: NA Intervention s ; studied: Hemodialysis and continuous ambulatory peritoneal dialysis Dates: NA Location: NA Recruitment setting: NA Exclusion criteria: NA Age: NA Sex: NA Race: NA Renal function at entry: NA Blood pressure at entry: NA Co-morbidities at entry: NA Other: Assumed that patients modeled have chronic kidney disease with stable decline in GFR.
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Generic Acetazolamide Acrivastine Astemizole Azathioprine Azelastine HCl Bimatoprost Brimonidine tartrate .20 % ; Brimonidine tartrate 0.15 % ; Brinzolamide Cetrizine Chlorambucil Cromolyn sodium Cyclophosphamide Cyclosporine gelatin capsules ; Cyclosporine microemulsion ; Daclizumab Dexamethasone suspension 0.1% ; Dexamethasone sodium phosphate 0.1% ; Diclofenac 0.1% Dipivefrin HCl Dorzolamide Dorzolamide hydrochloride timolol maleate Ebastine Emedastine difumarate Epinephrine HCl Etanercept Fexofenadine Fluorometholone acetate suspension 0.1% ; Fluorometholone suspension 0.1% or 0.25% ; Flurbiprofen 0.03% ; Infliximab Ketorolac 0.5 % Ketorolac tromethamine Ketotifen fumarate Latanoprost Levobunolol hydrochloride Levocabastine Common brand names Diamox Semprex-D Hismanal * Imuran Optivar Lumigan Alphaagan Alphahan P Azopt Zyrtec Leukeran Opticrom Crolom Cytoxan Sandimmune Neoral Zenapax Maxidex Decadron Voltaren Propine Trusopt Cosopt Kestine Emadine Epifrin Glaucon Enbrel Allegra Flarex eFlone Fluor-Op FML, FML Forte Ocufen Liquifilm Remicade Acular PF Acular Zaditor Xalatan Betagan Livostin Manufacturer Storz Glaxo Wellcome Inc. Janssen Pharmaceutica Inc. Faro Muro Pharmaceutical Allergan Pharmaceuticals Allergan Pharmaceuticals Allergan Pharmaceuticals Alcon Inc. Pfizer Inc. GlaxoWellcome Allergan Pharmaceuticals Bausch & Lomb Bristol-Myers Squibb Novartis Novartis Roche Alcon Inc. Merck & Co. Novartis Allergan Pharmaceuticals Merck & Co. Merck & Co. Rhone-Poulenc Rorer Alcon Inc. Allergan Pharmaceuticals Alcon Inc. Wyeth-Ayerst Aventis Alcon CIBA Vision CIBA Vision Allergan Pharmaceuticals Allergan Pharmaceuticals Centocor Allergan Pharmaceuticals Allergan Pharmaceuticals CIBA Vision Pharmacia & Upjohn Allergan Pharmaceuticals CIBA Vision Generic Lodoxamide Loratadine Loteprednol etabonate 0.2% ; Loteprednol etabonate 0.5% ; Methazolamide Methotrexate Methylprednisolone acetate Mizolastine Mycophenolate mofetil Naphazoline 0.05% ; Naphazoline 0.05% ; antazoline 0.5% ; Naphazoline 0.012% ; antihistamine Naphazoline 0.025% ; pheniramine maleate 0.3% ; Naphazoline 0.1% ; Naphazoline HCl Common brand names Alomide Claritin Alrex Lotemax Neptazane Rheumatrex Trexall Depo-Medrol Mizollen Cellcept Albalon Vasocon A Albalon A Naphcon A Naphcon Forte Vasocon Naphcon Clear Eyes Alocril Patanol Alamast Prefrin IsoptoCarpine Pilocar Pred Forte Econopred Inflamase Mild Vexol Prograf Seldane * Collyrium for Fresh Eyes Murine Plus Visine; Visine AC Betimol Timoptic Travatan Kenalog Aristocort Rescula Manufacturer Alcon Inc. Schering Corporation Inc. Bausch & Lomb Bausch & Lomb Wyeth Lederle Barr Laboratories Pharmacia & Upjohn Sanofi-Synthelabo Roche Allergan Pharmaceuticals CIBA Vision Allergan Pharmaceuticals Alcon Inc. Alcon Inc. CIBA Vision Alcon Inc. Abbott Laboratories Allergan Pharmaceuticals Alcon Inc. Santen Inc. Allergan Pharmaceuticals Alcon Inc. Iolab Allergan Pharmaceuticals Alcon Inc. CIBA Vision Alcon Inc. Fujisawa Hoechst-Marion Roussel Inc. Bausch & Lomb Abbott Laboratories Pfizer Inc. CIBA Vision Merck & Co. Alcon Inc. Bristol-Myers Squibb Fujisawa Novartis and
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Pediatric Use: In a well-controlled clinical study conducted in pediatric glaucoma patients ages 2 to 7 years ; the most commonly observed adverse events with brimonidine tartrate ophthalmic solution 0.2% dosed three times a day were somnolence 50% - 83% in patients ages 2 to 6 years ; and decreased alertness. In pediatric patients 7 years of age or older 20kg ; , somnolence appears to occur less frequently 25% ; . Approximately 16% of patients on brimonidine tartrate ophthalmic solution discontinued from the study due to somnolence. The safety and effectiveness of brimonidine tartrate ophthalmic solution have not been studied in pediatric patients below the age of 2 years. Brimonidine tartrate ophthalmic solution is not recommended for use in pediatric patients under the age of 2 years. Also refer to Adverse Reactions section ; . Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and other adult patients. ADVERSE REACTIONS Adverse events occurring in approximately 10-20% of the subjects included: allergic conjunctivitis, conjunctival hyperemia, and eye pruritis. Adverse events occurring in approximately 5-9% of the subjects included: burning sensation, conjunctival foliculosis, hypertension, oral dryness, and visual disturbance. Events occurring in approximately 1-4% of subjects included: allergic reaction, asthenia, blepharitis, bronchitis, conjunctival edema, conjunctival hemorrhage, conjunctivitis, cough, dizziness, dyspepsia, dyspnea, epiphora, eye discharge, eye dryness, eye irritation, eye pain, eyelid edema, eyelid erythema, flu syndrome, follicular conjunctivitis, foreign body sensation, headache, pharyngitis, photophobia, rash, rhinitis, sinus infection, sinusitis, stinging, superficial punctate keratopathy, visual field defect, vitreous floaters, and worsened visual acuity. The following events were reported in less than 1% of subjects: corneal erosion, insomnia, nasal dryness, somnolence, and taste perversion. The following events have been identified during post-marketing use of ALPHAGAN in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. The events, which have been chosen for inclusion due to either their seriousness, frequency of reporting, possible causal connection to ALPHAGAN, or a combination of these factors, include: bradycardia; hypotension; iritis; miosis; skin reactions including erythema, eyelid pruritis, rash, and vasodilation and tachycardia. Apnea, bradycardia, hypotension, hypothermia, hypotonia, and somnolence have been reported in infants receiving ALPHAGAN. OVERDOSAGE No information is available on overdosage in humans. Treatment of an oral overdose includes supportive and symptomatic therapy; a patent airway should be maintained.
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Hirsch JK, Gamble S, Conwell Y. Source : J Affect Disord. 2006 Jul 8; [Epub ahead of print] Related Articles, Links Background: Suicidal behavior is heterogeneous; suicide attempts can be impulsive lower planned ; or reflect forethought and preparation higher planned ; . Lower planned and higher planned attempts may have different correlates that require different prevention strategies. Based on a model of suicide planning relevant to middle-aged and older adults, we tested the following hypotheses: physical illness burden, decreased functional capacity, hopelessness, and living alone are associated with suicide attempts that are more extensively planned; lower cognitive functioning is associated with suicide attempts that are more impulsive. Methods: Subjects were 117 inpatients ages 50 and over diagnosed with major depression based on semi-structured clinical research interviews, the medical record, plus other records when available. All subjects had attempted suicide within 1 month of admission. The degree of planning prior to the suicide attempt was quantified using Beck's Suicide Intent Scale. Multivariate linear regression analysis identified correlates of planning. Results: As hypothesized, lower cognitive functioning was associated with lower levels of planning. Contrary to the hypothesis, impaired physical self-care was associated with lower not higher ; planning. Results pertaining to living alone were equivocal. Limitations: The study was limited by the cross-sectional research design and unclear generalizability to completed suicide or to racial ethnic minorities. Conclusions: Depressed patients with lower cognitive functioning and impairments in physical self-care may be especially vulnerable to impulsive suicidal behavior. The potential role of living alone in higher planned suicidal acts requires further investigation, for instance, xlphagan t.
Drug Name 1% 0.125% 0.5% Drug Tier 2 Requirements Limits PA PA PA INFLAMASE FORTE INFLAMASE MILD LOTEMAX MAXIDEX PRED FORTE PRED MILD prednisol prednisolone acetate prednisolone sodium 1% phosphate VEXOL 1% OPHTHALMOLOGY STEROID-SULFONAMIDE COMBINATIONS BLEPHAMIDE 10-0.2% BLEPHAMIDE S.O.P. 10-0.2% FML-S 10%-0.1% sulfacetamide w10-0.25% prednisolone OPHTHALMOLOGY SULFONAMIDES BLEPH-10 10% ocusulf-10 10% sulfac 10% sulfacetamide sodium 10% sulfacetamide sodium OPHTHALMOLOGY SYMPATHOMIMETICS ALPHAGAN P 0.15% 0.2% brimonidine tartrate 0.1% dipivefrin hcl IOPIDINE 0.5.
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Cancer Clinic ; in Hamilton. She said she went along with that to show everyone that it's OK because it's "just one of life's little bumps, and that we her family ; could get through it." The recommendation of the doctors at the Cancer Clinic was to go through six months of chemotherapy chemo ; , just to make sure they got all the cancer. However, she said she was feeling well after the surgery and now the doctors were asking her to go through a process that was going to make her sick. "Now it is time to cry. I was hoping to bring Mallory her baby ; home from her grandparents, so I would be her mom again instead of a visitor." She said the doctor gave her a week to make a decision, but the choice is not just to say yes or no; the choice was about whether to live or die. In July 1996, her chemotherapy began. She went to the Cancer Clinic alone and sat in a LAZ Boy chair and was administered drugs with names "so long and complicated that I can't even pronounce, with a list of side effects that were even longer." She said she went home after her 90minute treatment and around 10: 30 that night she began to vomit and retch. This Thersa Bachura, top right, survived lung-associate cancer went on for two hours until she was total- and is no longer able to work. She says, "at least I'm Photo courtesy Bachura family ly exhausted. In the house watching all of alive." this unfold were her eldest daughter and She said this question still remain: "Is this worth son, along with her son's girlfriend, none of whom it, to go through all of this?" With each passing day knew what to do for her. her stamina increased, her strength started to come "I'm crying now. I'm in so much pain and exhaustback and she began to enjoy the simple things in ed." life. She said from what she was told later by her famShe said her youngest daughter came home at the ily, she was delirious, crying and hallucinating. She age of 10 months. said her family was so frightened and didn't know It has been five years since her treatment and every what to do, they called for help, calling her husband day that passes without a recurrence means the less at work and her brother, an ambulance attendant, possibility of a relapse. She still has to take a lot of and doctors. Her family continued to watch over her medication and is no longer allowed to work because throughout the night. She said she finally fell asleep she can't physically do it. and that was "the end of the first day of the rest of She said, "At least I'm alive." my life." If she could give a message to others, she said, it The treatments continued for five months. Because would be to make informed and wise choices when of her violent reaction to the chemo, she was hospitalized for the rest of her treatments. The side effects of you are young "because if you don't, it may come the chemo were not the only problem, however. She back to haunt you. And don't think you're invincisaid she was hospitalized for a blockage in her bowels, ble, because you are not, even if you would like to had two blood clots lodged in her good lung and all her believe you are." hair fell out just after the treatment. Thersa Bachura is Christene Wilde's mother.
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