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As discussed in the main paper, the observed behavioral pattern of results in medicated and nonmedicated PD patients was predicted by our computational model 2 ; . To explicitly compare these results to the model, we simulated the probabilistic selection task in with three model manipulations intact, simulated PD, and simulated DA medication, as described in the main paper ; . 25 networks with different sets of random initial synaptic weights were run with each manipulation. Following training, Go NoGo associations were recorded from the model's striatum in response to input stimuli A and B Figure 2c in the main paper ; . For positive Go learning, we computed Go - NoGo associations for stimulus A. For negative NoGo learning, we computed NoGo - Go associations for stimulus B. We then performed a GLM exactly as in the behavioral analyses. This analysis revealed a highly significant interaction between stimulus condition and the contrast between simulated medication and simulated PD F[1, 72] 20.1, p .0001 ; . This is similar to the behavioral interaction observed between choosing A and avoiding B and the ON OFF medication contrast in PD patients. Networks with simulated DA medication had significantly higher overall Go associations for stimulus A then did networks with simulated PD [F 1, 72 ; 13.6, p .0004]. Conversely, PD networks had greater NoGo associations for stimulus B than did those with simulated medication [F 1, 72 ; 9.2, p .003]. The observed significant differences between simulated PD and medication networks in Go NoGo learning could result either from enhancements or impairments in the respective conditions or both ; . To disentangle these possibilities, we performed separate planned comparisons that compare Go NoGo associations of each of the DA manipulations networks to those of the intact networks. Compared with intact networks, simulated PD resulted in significantly lower Go associations to stimulus A [F 1, 48 ; 7.8, p .0075], with non-significantly greater NoGo associations to stimulus B [F 1, 48 ; 0.93, n.s.]. Conversely, networks with simulated DA medication had significantly weaker NoGo associations to stimulus B [F 1, 48 ; 4.33, p .04], and numerically but not significantly stronger Go associations to stimulus A [F 1, 48 ; 0.75, n.s.], for example, bunco prilosec.

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There are few studies of provider acceptability of medical abortion. Winikoff Winikoff 1995 ; reviewed some early studies that we have not been able to obtain. Marwick Marwick 1994 ; , in a report on nurses in Aberdeen, apparently suggested that the introduction of medical abortion to a clinic already providing surgical abortion can alter job satisfaction because of adjustments in tasks. The report suggested that providers should allow staff to redistribute their functions so that those who prefer to be more or less ; involved with medical abortion patients can seek suitable assignments. This is probably even more relevant in a service providing second trimester abortions.

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