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Pharmacodynamics: administration of enalapril maleate to patients with hypertension of severity ranging from mild to severe results in a reduction of both supine and standing blood pressure usually with no orthostatic component.
Post-hospitalisation psychological treatment Following inpatient weight restoration, people with anorexia nervosa should be offered outpatient psychological treatment that focuses both on eating behaviour and attitudes to weight and shape, and on wider psychosocial issues, with regular monitoring of both physical and C psychological risk. The length of outpatient psychological treatment and physical monitoring following inpatient weight restoration C should typically be at least 12 months. Additional considerations for children and adolescents with anorexia nervosa Family interventions that directly address the eating disorder should be offered to children and adolescents with anorexia B nervosa. Children and adolescents with anorexia nervosa should be offered individual appointments with a healthcare professional separate from those with their family members C or carers. The therapeutic involvement of siblings and other family members should be considered in all cases because of the C effects of anorexia nervosa on other family members. In children and adolescents with anorexia nervosa, the need for inpatient treatment and the need for urgent weight restoration should be balanced alongside the educational C and social needs of the young person. PHARMACOLOGICAL INTERVENTIONS FOR ANOREXIA NERVOSA There is a very limited evidence base for the pharmacological treatment of anorexia nervosa. A range of drugs may be used in the treatment of comorbid conditions but caution should be exercised in their use given the physical vulnerability of many people with anorexia nervosa. Medication should not be used as the sole or primary C treatment for anorexia nervosa. Caution should be exercised in the use of medication for comorbid conditions such as depressive or obsessive compulsive features as they may resolve with weight gain C alone.
NAMISA's education committee has been working on a 20 minute community presentation to offer to service groups and other organizations. The committee is looking for individuals who have a personal story to share. If you are interested in serving as a facilitator or in serving on the panel to recount your experiences, please contact Norma Carlson at 296-2612. Non-fiction author Pete Earley's latest book, Crazy, is available in the NAMISA library. The former investigative reporter for the Washington Post recounts his struggles navigating the criminal justice and mental health systems with his mentally ill son. Earley attended this year's NAMI national convention and read several passages from his book during the workshop on decriminalizing mental illness, for instance, barrington orthopedics!
Orthotic appliances" means a device or brace prescribed by a physician or other licensed practitioner within the scope of his her practice as defined by State law for the purpose of providing support, increased function, and overcoming physical impairment or defects. a. a brace includes rigid and semi-rigid devices used for the purpose of supporting a weak or deformed body member or restricting or eliminating motion in a diseased or injured part of the body.
Abstract. For humans, faces are highly overlearned stimuli, which are encountered in everyday life in all kinds of poses and views. Using psychophysics we investigated the effects of viewpoint on human face recognition. The experimental paradigm is modeled after the inter-extra-ortho experiment using unfamiliar objects by Blthoff and Edelman [5]. Our results show a strong viewpoint effect for face recognition, which replicates the earlier findings and provides important insights into the biological plausibility of viewbased recognition approaches alignment of a 3D model, linear combination of 2D views and view-interpolation ; . We then compared human recognition performance to a novel computational view-based approach [29] and discuss improvements of view-based algorithms using local part-based information and oxycodone.
Membranes. These will be different in neurons as compared to thymocytes, and different yet in other types of cells. Our results suggest that low or submicromolar concentrations of some ortho-substituted PCBs alter membrane structure, and indicate that this is accompanied by an increase in membrane fluidity as well as accompanying disruption of plasma, mitochondrial and endoplasmic reticulum membrane functions. This may be the mechanism whereby ortho-substituted PCBs alter the function of a variety of cells. The fact that not all cell types are affected similarly or at the same concentration may reflect differences in lipid composition and membrane proteins.
FIG. 7. Effects of local TTX on Schafferevoked AP initiation in the intact animal. Twin or 3 electrode pipette assemblies were used to eject TTX blue barrel in the left schemes ; and simultaneously record from near vertical loci within the same neuron subset. A and B: sample tracings and evolution of PS amplitude, respectively, in representative experiments. Blue tracings and arrows correspond to TTX application. When TTX was ejected at the proximal basal dendrites 1 ; , the antidromic PS at the soma layer decreased E ; , but not the synaptically evoked PS F ; . Basal backpropagation reduced in the 2 cases , and OE ; . When TTX was ejected at the soma 2 ; , the antidromic , ; , and to a lesser extent, the orthodromic, somatic PSs OE ; decreased. Backpropagation was greatly attenuated E ; , while the orthodromic dendritic PS was unchanged F ; , showing apical initiation of APs. Apical ejection of TTX 3 ; caused the abolition of the local dendritic PS F ; and a strong reduction of the somatic PS OE ; . The antidromic PS remained unchanged , ; . Experiment in 3 is from a different animal than 1 and 2 and oxycontin.
Janssen-Ortho v. The Minister of Health fentanyl transdermal patch DURAGESIC , February 9, 2004 Court of Appeal dismisses Janssen-Ortho's appeal from an applications judge's decision. The judge had dismissed its application for judicial review of a Minister's decision to remove a patent from the Patent Register, finding that the DURAGESIC patch in particular, the release membrane, the drug reservoir, and the backing ; does not fall within the definition of "medicine" for the purposes of the Regulations. Court of Appeal decision 2004 FCA 62 ; Motions Judge's decision 2003 FCT 286.
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Conditions of Use: Limited to one ACIPHEX free trial voucher redemption per person. Eisai Inc. and Ortho-McNeil, Inc. reserve the right to rescind, revoke, or amend this offer at any time without notice. This voucher is not valid through mail order pharmacies. Subject to eligibility restrictions listed on the bottom of this voucher. I certify that: i ; I have dispensed the ACIPHEX product to an eligible patient, ii ; I have not submitted and will not submit a claim for reimbursement to the patient or any third-party payer, and iii ; my participation in this program complies with all applicable laws and contractual or other obligations I have as a pharmacy provider. Pharmacist's signature Utilize the following codes for processing: BIN # 61 0 5 2007 Eisai Inc. and Ortho-McNeil, Inc. May 2007 and penicillin.
Established relative efficacy of the agents for treatment. Established efficacy in a large animal model an FDA requirement ; . Established efficacy under GMP and GLP conditions an FDA requirement ; . Secured commitment of a relevant pharmaceutical company. Figured out the mechanism.
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Discontinued the use of Samento for 10 days but at the next control test the PSA was back to 50 already. Later on the treatment proceeded with a 2 x dosage of Samento 600 mg mornings and evenings half an hour before meals with a cup of warm Rooibos tea ; . The last control test from April 26, 2002 shows the tumor marker is normal - 1.75. The patient feels excellent. The treatment dose depends on the goal we've set as well as the information we have about the patient. If we are going to treat a common flu no matter whether type A, B or a new mutant form ; , 3 to 4 600mg capsules daily are enough for the patient to forget about the muscle and joint pain, the running nose and the fever already on the third day. Then the dosage can be reduced to 2 x capsules for another 5 to 6 days and if no complications appear the patient can continue taking 1 capsule daily for about a month as a maintenance dosage. In some cases the maintenance, prevention and treatment dose can prove identical. Of course such cases are rare but they still exist. One capsule of Samento 120 mg daily is an excellent prevention dose against the flu, common cold and other similar troubles. However the same dosage proved entirely sufficient to cure in just a month a grave stomach condition in a 52-year-old woman that didn't recede to the latest therapies applied in such cases not only in Bulgaria but also in the USA and the entire developed world. I'll tell you about this case in more detail some other time. There are quite a lot of examples for combating one and the same disease with a 2 x maximum ; dosage of Samento 600 mg in one patient, and not achieving anything even with the maximum 3 x 2 dose being applied for a whole 3 months in another patient. And the disease is not even cancer!? How many more unknowns does Samento hide? I can only tell, on the base of my former experience of treating over 3000 people with Samento, that this herb has many more useful properties than we know and than we can suppose. It is the greatest example that the human health is more in the nature, whose part are also we people, than in the modern civilization that too often ruins men instead of strengthening their health, for instance, cyclen lo ortho tri.
REHABILITATION. QUALITATSGEMEINSCHAFT MEDIZINISCHE REHABILITATION IN SCHLESWIG-HOLSTEIN - HAUPTSTUDIE UND ERGEBNISSE AUS ORTHOPADISCHEN KLINIKEN - Deck R. and Raspe H. [Dr. R. Deck and phenergan.
Date: 11 21 00ISR Number: 3615619-5Report Type: Expedited 15-DaCompany Report #JRFBEL2000002722 Age: 38 YR Gender: Male I FU: I Outcome Dose Duration Death Required Intervention to Prevent Permanent 7.5 MG, Impairment Damage DAILY, 2 DAY PT Blood Creatine Phosphokinase Increased Myoglobin Blood Increased Myoglobinuria Pulmonary Haemorrhage Renal Impairment Renal Tubular Disorder DAILY 2 DAY Respiratory Failure Rhabdomyolysis 1500 MG M2, 22-Aug-2005 Page: 370 10: 49 Ifosfamide Ifosfamide ; SS Flunitrazepam Flunitrazepam ; Report Source Foreign Literature Health Professional Product Haldol Role PS Manufacturer Rw Johnson Pharmaceutical Research Institute Div 9rtho Pharm Route.
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2001 sep; 137 9 ; : 1196- callen jp, hughes ap, kulp-shorten division of dermatology, department of medicine, university of louisville, 310 e broadway, suite 200, louisville, ky 40202, usa jefca aol background: subacute cutaneous lupus erythematosus is a nonscarring, non-atrophy-producing photosensitive cutaneous disorder.
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Members who don't utilize the services of a PPO provider will be reimbursed at the non-preferred provider schedule. Orthodontic services cease upon the dependents 19th birthday, not the completion of the treatment. The SBA orthodontics program covers only Level 2 and 3 malocclusions, which cause interference with normal functions and
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1. Antidepressants A. Cyclic antidepressants 1. Mechanisms: all tricyclics inhibit serotonergic and or noradrenergic reuptake; clinical benefits often begin after 2-3 weeks of treatment. 2. Adverse effects: anticholinergic reactions dry mouth, constipation, blurred vision, prolonged gastric emptying, urinary retention cardiac effects tachycardia, T-wave flattening or inversion, prolongation of the PR, QRS, QT intervals other effects orthostasis, sedation, extrapyramidal syndromes, weight gain, sexual dysfunction, jaundice, leukopenia, rashes ; . 3. Withdrawal: may manifest as anxiety, fever, sweating, myalgia, nausea, headache, vomiting, dizziness, dyskinesia, akathisia. 4. Anesthetic considerations: may increase anesthetic requirements secondary to increased brain catecholamine activity potentiation of centrally acting anticholinergic agents may increase postoperative confusion; may see exaggerated response to both indirect-acting vasopressors and sympathetic stimulation. B. Monoamine oxidase inhibitors 1. Mechanisms: blocks the enzyme monoamine oxidase, thus inhibiting the breakdown of monoamines; results in increased neurotransmitters epinephrine, norepinephrine, and dopamine; requires 2 weeks to achieve inhibition and 2-4 weeks for clinical effects. 2. Adverse effects: orthostatic hypotension, agitation, tremor, seizures, muscle spasms, urinary retention, paresthesias, jaundice, tyramine-induced hypertensive crisis e.g., some cheeses, chianti wine, chocolate, liver, fava beans, avocados exaggerated response to indirect-acting sympathomimetics; interaction with opioids may cause excitatory or depressive reactions; excitatory reaction thought to be central serotonergic overactivity manifesting as hypertension, hypotension, tachycardia, diaphoresis, hyperthermia, muscle rigidity, seizures, coma; meperidine has been associated with fetal excitatory reactions inhibition of hepatic enzymes 3. Anesthesia considerations: discontinuation of MAO inhibitors preop is controversial and should be guided by the patient's dependence on these drugs; avoid opioids if possible morphine is the preferred narcotic avoid ketamine and pancuronium. C. Selective serotonin reuptake inhibitors SSRIs ; 1. Mechanisms: blockade of the presynaptic serotonin reuptake pump. 2. Adverse effects: may cause headaches, stimulation or sedation, fine tremor, tinnitus, rare extrapyramidal symptoms dystonia, akathisia, dyskinesia, tardive dyskinesia ; , nausea, vomiting, diarrhea, sexual dysfunction; overall fewer side effects then other antidepressants and potassium and ortho.
For specific advice refer to manufacturer's recommendations Item Auroscope ear pieces How often After use Method If soiled, remove wax by cleaning with generalpurpose detergent and warm water 350C ; , using a thin brush to clean inside. Then disinfect by: a ; Immersing in 70% alcohol for 10 minutes or b ; Pulling through the lumen a 70% alcohol impregnated swab or c ; Autoclave to sterilise Brushes should be cleaned and dried or discarded Protect from soiling with paper roll. Clean with detergent and water if soiled or Wipe with an alcohol impregnated cloth Clean with detergent and water, or cream cleaner, rinse and leave to dry As for basins and taps Remove from bath surface. Immerse in warm water and detergent and agitate well. After each use hang mat reverse side up to dry over the side of the bath. Follow any specific manufacturer's instructions to clean baths and showers. Spa baths, Jacuzzis etc require disinfecting procedures. Wash with warm water and detergent, dry Wash with warm water and detergent, dry Disinfect bedpans urinals using a washerdisinfector, OR Use disposables and discard in a macerator or as low-risk clinical waste, OR If re-usable wash with detergent and warm water, rinse with very hot water and dry using disposable paper towels. Clean with detergent and water Clean with warm water and detergent. Rinse with hot water. Store dry, inverted, and above floor level. Wash with hot water and detergent. Dry and store upside down. Line with plastic before use, then clean as above Vacuum daily. There should be a schedule for cleaning carpets at least six monthly. The type of floor covering should be chosen to enable it to be cleaned regularly. Spills of body substances should be removed using a disposable paper towel wear gloves for this ; and then cleaned with carpet shampoo Discard single use bags every morning Drain re-usable bags daily; protect the cap. Change weekly or when soiled. Individualise catheter stands. Clean with detergent and water.
BACTERIA `Good' bacteria in the gut can be encouraged by eating live natural yoghurt or taking Acidopholus in tablet form. This is one way of trying to counteract the negative effects of taking antibiotics and steroids. BONE SCAN See also OSTEOPOROSIS ; You may need a bone scan if you have been on oral steroids for some time, as they deplete bone density. If you are diagnosed with osteoporosis you should look at the website of the National Osteoporosis Society for information nos ; . Many of their leaflets are to be found in the Orthopaedics Departments in hospitals. BRITISH LUNG FOUNDATION This organisation can provide help with breathing problems and they run support groups called Breathe Easy Groups which Aspergillus patients could usefully join. There is also a Pen Pals Breathe Easy Group, and a Baby Breathe Easy network is being developed. There is plenty of useful information here on things such as a bronchoscopy and a nebuliser. lunguk and pravachol.
This selection from the emedtv web site takes a closer look at generic zonegran, including information on how the generic version of the drug compares to the brand-name version.
In this study, we found that a significant number of patients 381 [21 percent] of 1, 800 ; were receiving antidepressant therapy for diverse medical conditions. This is important information for dental practice because of the potential for adverse effects, including xerostomia, orthostatic hypotension and interaction with vasoconstrictors, as well as the possibility that these effects may be increased by other, concurrently administered, medications. Consequently, dentists must take appropriate precautions when treating these patients. s.
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Choosing between treatment strategies for gastroesophagael reflux disease. Med Decis Making 2002; 22: 290308. Lhatoo SD, Sander JWAS, Shorvon SD. The dynamics of drug treatment in epilepsy: an observational study in an unselected population based cohort with newly diagnosed epilepsy followed up prospectively over 1114 years. J Neurol Neurosurg Psychiatry 2001; 71: 6327. Billingham LJ, Abrams KR, Jones DR. Methods for the analysis of quality-of-life and survival data in health technology assessment. Health Technol Assess 1999; 3 10 ; . 272. Abbott Laboratories. An open-label extension study of tiagabine HCl in the treatment of patients with partial seizures. Abbott Park, IL: Abbott Laboratories; 1998. 273. Office for National statistics. Mortality statistics: general. Review of the Registrar General on deaths in England and Wales, 2000. London: Office for National Statistics; 2000. 274. Ades A. A chain of evidence with mixed comparisons: models for multi-parameter evidence synthesis and consistency of evidence. 2002. URL: : ihs.ox.ac herc DEEM Ades . Accessed February 2003. 275. Netten A, Curtis L. Unit costs of health and social care. PSSRU, University of Kent; 2002. URL: : \\ ukc.ac PSSRU. Accessed February 2003. 276. Department of Health. NHS Executive. The new NHS: 2002 reference costs. Department of Health; 2002. URL: : doh.gov nhsexec refcosts #spred. Accessed February 2003. 277. Lhatoo SD, Johnson AL, Goodridge DM, MacDonald BK, Sander JWAS, Shorvon SD. Mortality in epilepsy in the first 11 to 14 years after diagnosis: multivariate analysis of a longterm, prospective, population-based cohort. Ann Neurol 2001; 49: 33644. Wilton LV, Stephens MDB, Mann RD. Visual field defect associated with vigabatrin: observational cohort study. BMJ 1999; 319: 11656. NHS North West Clinical Neuroscience Partnership. Clinical framework for the management of adults with epilepsy. A North West Clinical Framework. Manchester: North West Clinical Neuroscience Partnership; 2001. 280. Johannesson M, Weinstein S. On the decision rules of cost-effectiveness analysis. J. Health Econ. 1993; 12: 45967. Van Hout BA, Al MJ, Gordon GS, Rutten FF. Costs, effects and C E-ratios alongside a clinical trial. Health Econ 1994; 3: 30919, because orho wheeless.
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IDIOPATHIC THROMBOCYTOPENIA PURPURA ITP ; : Also idiopathic immune thrombocytopenic purpura. A condition in which the body produces antibodies against the platelets in the blood, which are cells responsible for blood clotting. ITP is very common in persons infected with HIV. IL-1 INTERLEUKIN-1 ; : A cytokine that is released early in an immune system response by monocytes and macrophages. It stimulates T-cell proliferation and protein synthesis. Another effect of IL-1 is that it causes fever. IL-2 INTERLEUKIN-2 ; : A cytokine secreted by Th1 CD4 cells to stimulate CD8 Tlymphocytes. IL-2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, IL-2 production gradually declines. Use of IL-2 therapy is under study as a way to raise CD4 cell counts and restore immune function. IL-4 INTERLEUKIN-4 ; : A cytokine secreted by The CD4 cells that promotes antibody production by stimulating B-cells to proliferate and mature. IL-12 INTERLEUKIN-12 ; : A cytokine released by macrophages in response to infection that promotes the activation of cell-mediated immunity. Specifically, IL-12 triggers the maturation of Th1 CD4 cells, specific cytotoxic T-lymphocyte responses, and an increase in the activity of NK cells. IL-12 is under study as an immunotherapy in HIV infection. IMMUNE COMPLEX: Clusters formed when antigen and antibody bind together. IMMUNE DEFICIENCY: A breakdown or inability of certain parts of the immune system to function, thus making a person susceptible to certain diseases that they would have not contracted with a healthy immune system. IMMUNE RESPONSE: The activity of the immune system against foreign substances. IMMUNE SYSTEM: The body's complicated natural defense against disruption caused by invading microbes and cancers. There are two aspects of the immune system's response to disease: innate and acquired. The innate part of the response is mobilized very quickly in response to infection and does not depend on recognizing specific proteins or antigens foreign to an individual's normal tissue. It includes complement, macrophages, dendritic cells, and granulocytes. The acquired, or learned, immune response arises when dendritic cells and macrophages present pieces of antigen to lymphocytes, which are genetically programmed to recognize very specific amino acid sequences. The ultimate result is the creation of cloned populations of antibodyproducing B cells and cytotoxic T-lymphocytes primed to respond to a unique pathogen and
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Cases include class allegations, the test-case approach resolves the claims as to the named parties, ends the tolling of the statute of limitations, and requires potential litigants to file lawsuits if they wish to pursue claims.1146 Potential disadvantages of using test cases include the lack of any clear preclusive effect of a judgment for defendants, possible limits on the preclusive effects of judgments for the plaintiffs, and the possibility of creating "chaos among plaintiffs' counsel"--that is, lead counsel appointed to represent plaintiffs in the MDL proceedings.1147 On the other hand, the Honda American MDL transferee court decided that an issues class action approach would yield a mutual preclusive effect and would "serve to keep the leadership structure among plaintiffs' counsel in place."1148 The transferee judge usually supervises discovery, decides motions, and, if called for, decides whether to certify a class action.1149 Under the decentralized approach, the transferee judge would then remand the cases to their original districts for trial, as in the breast implant and orthopedic bone screw litigations.1150 In other cases, grants of summary judgment or approvals of settlement have obviated remand to the transferee courts.1151.
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The IASUSA is committed to providing HIV and AIDS practitioners with our most recent information and treatment guidelines. The site includes: New and revised listings of HIV drug resistance mutations figures IASUSA publications available online, including clinical guidelines and Topics in HIV Medicine Calendar of events, including annual cosponsored sessions at scientific meetings Detailed information about IASUSA CME courses CME course registration forms The IASUSA mail list sign-up form Visit us at.
More than two thirds of hospital leaders thought that a mandatory, nonconfidential reporting system run by the state would discourage reporting of patient safety incidents to their hospital's own internal reporting system TABLE 2 ; . Only 8% thought it would encourage internal reporting, and there were no differences by type of state event reporting system. Overall, about three quarters of hospital leaders 79% ; thought that such a system encouraged lawsuits against hospitals, although this number was lower among respondents from the states having a mandatory, nonconfidential system P .01 ; . Most respondents 73% ; thought that a mandatory system would have either no effect or a negative effect on actual patient safety within their own state. Hospital leaders in our sample were strongly supportive of policies that kept confidential the names of the hospi.
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1. Ganong WF. Review of medical physiology. New York: Lange Medical Books McGraw-Hill, 1999, p. 691 693. 2. Guyton AC and Hall JE. Human Physiology and Mechanisms of Disease. Philadelphia, PA: Saunders, 1997, p. 236 241. 3. Jackson BA and Ott CE. Renal System. Madison, CT: Fence Creek Publishers 1999, p. 84 90.
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Has been linked to hepatotoxicity, pulmonary toxicity, carcinogenicity, and tumor promotion Yost, 1989; Thompson et al., 2001; Monks and Jones, 2002 ; . Protein covalent binding has been observed with drugs that are generally considered safe captopril, aspirin, valproic acid ; , as well as drugs that have been associated with hepatic impairment acetaminophen overdose ; and idiosyncratic or allergic reactions diflunisal and zomepirac ; Uetrecht, 1992; Pumford and Halmes, 1997 ; . Although the biological consequences of this P450 activation pathway of BMS-204352 are unknown, no toxicological findings directly attributable to its protein covalent binding have been observed with the compound in rats. In summary, within an hour of dosing rats with [14C]BMS-204352, over two-thirds of the drug related material radioactivity ; in plasma is covalently bound to plasma proteins. The covalently bound adduct of BMS-204352 in rat plasma results from O-demethylation and replacement of the ring-fluorine atom of [14C]BMS-204352 by -amino group of a lysine residue in proteins. Metabolic activation of BMS-204352 appears to proceed through an ortho-quinone methide, which is formed by P450-mediated O-demethylation and spontaneous loss of hydrogen fluoride. The toxicological consequences of the protein covalent binding observed with BMS-204352 are presently unknown. Acknowledgments. We thank Dr. Dave Detlefsen for providing.
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Table C-1 SEX HORMONES CATEGORY ORAL CONTRACEPTIVES OCs ; Lo-Ovral, Ortjo Novum, Brevicon, Modicon, Norinyl, Genora, Tri-levlen, etc. ; .Nausea, HA, edema, weight gain, intraoral soft tissue changes gingivitis ; [if dental antibiotics are taken for 48 hours or more, advise additional barrer contraception for the remainder of the pill pak.] -Progestin causes increased inflammatory response to plaque -Increased dry socket for 21 28 days -OC effect decreased by Ampicillin Amoxicillin Tetracyclines -BZDP will have longer activity with OCs -Oral mucosa is more resistant to trauma ADVERSE EFFECTS TREATMENT IMPACT.