The Chest Physician should always be consulted. 3.8 Whooping Cough Bordetella pertussis Erythromycin: up to 2 years 125mg 3-8 years 250mg 3.9 Bronchiolitis in Children Mainly respiratory syncytial virus Ribavirin aerosol 3.10 20mg ml by inhalation 12-18 hours per day QDS QDS PO PO 14 days 14 days.
Return to top erythromycin is an antibiotic used to treat many kinds of infections, including: acute pelvic inflammatory disease gonorrhea intestinal parasitic infections legionnaires' disease listeriosis pinkeye rectal infections reproductive tract infections skin infections syphilis upper and lower respiratory tract infections urinary tract infections whooping cough erythromycin is also prescribed to prevent rheumatic fever in people who are allergic to penicillin and sulfa drugs.
This chapter is adapted from the Canadian Pandemic Influenza Plan Health Canada, Feb. 2004.
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Background: Chlamydia trachomatis exposure at birth may cause conjunctivitis or pneumonia. Until recently, a course of oral erythromycin prophylaxis was recommended for C trachomatisexposed neonates. However, recognition of an association between erythromycin and pyloric stenosis prompted a change to a watchful waiting recommendation under which only infants who develop symptomatic C trachomatis infection are treated with oral erythromycin. Objective: To compare erythromycin prophylaxis with.
Antibiotic drug resistance in acne has been documented for the last decade and is increasing in all parts of the world where it has been looked for. In Leeds the antibiotic drug resistance rose from 38% in 1992 to 68% in 1997. The antibiotic resistance was highest to erythromycin cross-reacting with clindamycin; this was also seen in tetracycline. The importance of drug resistance is however very difficult to evaluate. There is no doubt that patients continue to respond to antibiotics despite the fact that they carry resistant bacteria. It is possible that the use of topical or systemic antibiotics will achieve levels within the skin that can kill off even resistant bacteria. The problem however, will not go away and may become an important feature in our future management of the disease. The search for non-antibiotic alternatives is still very important.
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29. Bass JW, Freitas BC, Freitas AD, et al. Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. Pediatr Infect Dis J 1998; 17: 44752. Cascio A, Colomba C, Antinori S, et al. Clarithromycin versus azithromycin in the treatment of Mediterranean spotted fever in children: a randomized controlled trial. Clin Infect Dis 2002; 15: 34: Citterio F, Di Pinto A, Borzi MT, et al. Azithromycin treatment of gingival hyperplasia in kidney transplant recipients is effective and safe. Transplant Proc 2001; 33: 2134 Nash MM, Zaltzman JS. Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. Transplantation 1998; 65: 16115. Gruber F, Zamolo G, Saftic M, et al. Treatment of confluent and reticulated papillomatosis with azithromycin. Clin Exp Dermatol 1998; 23: 191. Weigl LB, Beham A, Schnopp C, et al. Confluent and reticulate papillomatosis. Successful therapy with azithromycin. Hautarzt 2001; 52: 9479. Raja Babu KK, Snehal S, Sudha Vani D. Confluent and reticulate papillomatosis: successful treatment with azithromycin. Br J Dermatol 2000; 142: 12523. Luft BJ, Dattwyler RJ, Johnson RC, et al. Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. Ann Intern Med 1996; 124: 78591. Strle F, Maraspin V, Lotric-Furlan S, et al. Azithromycin and doxycycline for treatment of Borrelia culture-positive erythema migrans. Infection 1996; 24: 64 Solera J, Beato JL, Martinez-Alfaro E, et al. Azithromycin and gentamicin therapy for the treatment of humans with brucellosis. Clin Infect Dis 2001; 32: 506 Duran JM, Amsden GW. Azithromycin: indications for the future? Expert Opin Pharmacother 2000; 1: 489 Maskell JP, Sefton AM, Williams JD. Comparative invitro activity of azithromycin and erythromycin against Gram-positive cocci, Haemophilus influenzae and anaerobes. J Antimicrob Chemother 1990; 25 Suppl A ; : 19 24. 41. Kitzis MD, Goldstein FW, Miegi M, et al. In vitro activity of azithromycin against various gram-negative bacilli and anaerobic bacteria. J Antimicrob Chemother 1990; 25 Suppl A ; : 158. 42. Goldstein EJ, Citron DM, Hunt Gerardo S, et al. Activities of HMR 3004 RU 64004 ; and HMR 3647 RU 66647 ; compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans. Antimicrob Agents Chemother 1998; 42: 112732. Retsema J, Girard A, Schelkly W, et al. Spectrum and mode of action of azithromycin CP-662, 993 ; , a new 15-membered-ring macrolide with improved potency against gram-negative organisms. Antimicrob Agents Chemother 1987; 31: 1939 Slaney L, Chubb H, Ronald A, et al. In vitro activity of azithromycin, erythromycin, ciprofloxacin and norfloxacin against Neisseria gonorrhoeae, Haemophilus ducreyi, and.
Sive isolate in children in our hospital during this period, was not isolated from these children. Sequential colonization by 2, 3 or SGTs was observed in 18, 5 and 2 children, respectively. Resistance to penicillin, chloramphenicol, cotrimoxazole and erythromycin was observed in 0, 13 6% ; 11 and 5 3 % ; isolates, respectively. There was a significant difference in susceptibility to cotrimoxazole between colonizing and invasive isolates 5 % vs. 40 %, P 0.0001 ; . Jelesic Z. et al. [Shigellae isolated in 1997--plasmid profiles and antibiotic resistance]. Med Pregl. 1998; 51 7-8 ; : 305-9.p Abstract: INTRODUCTION: Shigella spp is one of the most frequently isolated bacteria causing acute diarrhea with us. Genetics of pathogenicity of Shigella spp. includes chromosomal and plasmid genes. Most virulence factors are coded by invasion plasmid antigen genes residing on a 180-230 MDa plasmid. There is a big problem with multiple resistance of Shigella spp. strains, which is mostly plasmid-borne. Genetic analysis of bacterial cells, that is plasmid profile analysis, is important for investigation of sources and ways of spreading of the infection. All isolates originating from the same clone have identical plasmid profiles, i.e. number and size of plasmids. The aim of the investigation was: comparing the type of resistance to antimicrobical agents found in epidemic and nonepidemic. Shigella strains isolated in 1997, analyzing plasmid profiles of these isolates and confirming their epidemic connection. MATERIAL AND METHODS: Susceptibility to antibiotics was examined by a standard disc-diffusion method. Plasmid profiles of 40 strains 20 from the outbreak and 20 from sporadic cases ; were tested using a method of alkaline lysis by Birnboim and Doly followed by electrophoresis in agarose gel. RESULTS: Shigella strains were resistant to antimicrobial agents which are most commonly used. Epidemic isolates shared the same resistance type, they were resistant to cephalexin, streptomycin and co-trimoxazole. The dominant type of resistance of nonepidemic strains was to ampicillin, streptomycin and co-trimoxazole. Strains isolated during the outbreak had identical plasmid profiles 2 plasmid bands of 55 and 1.5 MDa ; . Non-epidemic isolates had different plasmid profiles as well as type of resistance. CONCLUSION: Strains of Shigella spp. isolated during an outbreak had the same type of resistance and the same plasmid profiles, which indicated their origin from the same clone.The plasmid profile analysis is a reliable and precise method for determination of epidemic connection of Shigella isolates. Jenkins S.G. et al. Synergistic interaction between ofloxacin and cefotaxime against common clinical pathogens. Infection. 1995; 23 3 ; : 154-61.p Abstract: Antimicrobial synergy resulting from combined antibiotic therapy is often important in the treatment of serious bacterial infections. To investigate the interactions between cefotaxime CTX ; , desacetylcefotaxime DES ; , and ofloxacin OFL ; , 247 recent clinical isolates were tested for in vitro susceptibility to each antibiotic alone by an agar dilution technique and retested with the various antibiotic combinations using a checkerboard protocol. Fractional inhibitory concentrations were calculated for all organisms with all drug combinations. Time kill kinetic studies were performed on selected isolates to examine the bactericidal activity of the various antimicrobial combinations. Of the 110 gram-negative organisms tested, synergy or partial synergy between CTX, DES and OFL was demonstrable for 89 81% ; . Included in the study were 70 members of the Enterobacteriaceae family, 20 isolates of Pseudomonas aeruginosa, 10 strains of Acinetobacter baumannii, and 10 isolates of Xanthomonas maltophilia. Additive activity was observed against an additional 13 11% ; isolates. Findings were similar for the 89 grampositive isolates examined. Organisms tested included methicillinresistant Staphylococcus aureus 20 ; , methicillin-susceptible Staphylococcus aureus 20 ; , methicillin-resistant Staphylococcus epidermidis 9 ; , methicillin-susceptible S. epidermidis 10 ; , Enterococcus faecalis 10 ; , and Streptococcus pneumoniae 20 ; . Synergy or partial synergy was observed against 81 91% ; . Less synergistic activity was detected, however, with members of the Bacteroides fragilis group. Of the 48 organisms tested, synergy or and floxin.
Erythromycin, clarithromycin biaxin ; , cimetidine pepcid ; and ketoconazole can increase the blood level of tegretol.
Ursula Nusgen, Mary Kelleher and Brian O'Connell Department of Microbiology, St. James's Hospital, Dublin Clindamycin is a useful agent for the treatment of infections caused by Staphylococcus aureus. Resistance occurs most commonly by acquisition of erythromycin resistance methylase genes erm ; that code for enzymes that methylate the 23S rRNA. Expression of erm may be constitutive or inducible, which may be detected by the clindamycin induction test CIT ; . The incidence of inducible and constitutive clindamycin resistance varies by geographic region and also between hospitals within a region. Between October 2003 and June 2004, susceptibility testing to erythromycin, clindamycin and a CIT was performed routinely by NCCLS methodology on clinical S. aureus isolates recovered from blood, sputum or wound specimens at St. James's Hospital. Overall, 712 of 1857 38.3% ; S. aureus isolates had a positive CIT indicating inducible resistance ; and 42 of 1880 2.2% ; displayed constitutive clindamycin resistance. 208 of 1212 17.2% ; methicillin susceptible S. aureus MSSA ; isolates were erythromycin resistant. 162 77.8% ; of these isolates had a positive CIT; 10 4.8% ; were both erythromycin and clindamycin resistant, 20 9.6% ; had a negative CIT and there was no CIT data on 16 isolates. 594 of 667 89.1% ; methicillin resistant S. aureus MRSA ; isolates were erythromycin resistant. 550 92.6% ; of these isolates had a positive CIT; 32 5.6% ; were both erythromycin and clindamycin resistant, 5 0.8% ; had a negative CIT, and there was no CIT data on 7 isolates. This study reports a high incidence of inducible clindamycin resistance ICR ; mainly among MRSA. Rates of ICR among community-onset MRSA need to be determined and fluoxetine.
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Technetium-99m labeled antimicrobial peptides discriminate between bacterial infections and sterile inflammations. Eur J Nucl Med. 2000; 27: 292301. Welling MM, Lupetti A, Balter HS, et al. 99mTc-labeled antimicrobial peptides for detection of bacterial and Candida albicans infections. J Nucl Med. 2001; 42: 788 Lupetti A, Welling MM, Pauwels EKJ, Nibbering PH. Radiolabeled antimicrobial peptides for infection detection. Lancet Infect Dis. 2003; 3: 223229. Nibbering PH, Welling MM, Paulusma-Annema A, van den Barselaar MT, Pauwels EKJ. Monitoring the efficacy of antibacterial treatments of infections with 99mTc-labeled antimicrobial peptides [abstract]. Nucl Med Commun. 2000; 21: 575576. Nibbering PH, Ravensbergen E, Welling MM, et al. Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria. Infect Immun. 2001; 69: 1469 de Koster HS, Amons R, Benckhuijsen WE. The use of dedicated peptide libraries permits the discovery of high affinity binding peptides. J Immunol Methods. 1995; 187: 179 Welling MM, Mongera S, Lupetti A, et. Radiochemical and biological characteristics of 99mTc-UBI 29 41 for imaging of bacterial infections. Nucl Med Biol. 2002; 29: 413 Calame W, van der Waals R, Mattie H, van Furth R. Effect of etoposide and cyclophosphamide on the efficacy of cloxacillin and erythromycin in an experimental staphylococcal infection. Antimicrob Agents Chemother. 1989; 33: 980 Geertsma MF, Broos HR, van den Barselaar MT, Nibbering PH, van Furth R. Lung surfactant suppresses oxygen-dependent bactericidal functions of human blood monocytes by inhibiting the assembly of the NADPH oxidase. J Immunol. 1993; 150: 23912400.
15. Solifenacin Potent 3A4 Inhibitors Alert Message: The daily dose of Vesicare solifenacin ; , a CYP 3A4 substrate, should not exceed 5 mg when coadministered with a potent CYP3A4 inhibitor e.g. ketoconazole, itraconazole, ritonavir, nelfinavir, clarithromycin, and nefazodone ; . Exceeding the recommended dose during concurrent therapy may increase the risk of adverse effects. Conflict Code: DD Drug Drug Interaction Drug Disease: Util B Util C Util A Darifenacin Ketoconazole Erytjromycin Itraconazole Troleandomycin Ritonavir Indinavir Nelfinavir Clarithromycin Nefazodone Max Dose: 5 mg day References: Facts & Comparisons, 2005 Updates. Vesicare Prescribing Information, Nov. 2004 GlaxoSmithKline and
metformin.
Drug Aminoglycosides Gentamicin Tobramycin Penicillins Ampicillin Penicillin G Ampicillin Sulbactam Unasyn ; Ticarcillin Clav. Acid Timentin ; Piperacillin Tazo Zosyn ; Cephalosporins Cefazolin Ancef Kefzol ; Cefotetan Cefotan ; Cefuroxime Zinacef ; Cefoxitin Mefoxin ; Cefotaxime Claforan ; Ceftriaxone Rocephin ; Ceftazidime Fortaz ; Others Aztreonam Azactam ; Clindamycin Cleocin ; Erythromyycin Doxycycline TMP SMX Bactrim Septra ; Vancomycin Vancocin ; IV TO PO CONVERSION Dosing 80mg Q8H or 240mg Q24H 80mg Q8H or 240mg Q24H.
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Ensure the availability of pharmaceutical decision support. Make relevant patient information available at the point of care and ilosone.
Clin neuropharmacol 20 : 13-2 1997, for instance, efythromycin and alcohol.
1. Workowski KA, Berman SM, for the Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2006 [Published correction appears in MMWR Recomm Rep 2006; 55: 997]. MMWR Recomm Rep 2006; 55 RR-11 ; : 1-94. Accessed March 8, 2007, at: : cdc.gov mmwr PDF rr rr5511 . 2. Andrews WW, Klebanoff MA, Thom EA, Hauth JC, Carey JC, Meis PJ, et al., for the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Midpregnancy genitourinary tract infection with Chlamydia trachomatis: association with subsequent preterm delivery in women with bacterial vaginosis and Trichomonas vaginalis. J obstet Gynecol 2006; 194: 493-500. olshen E, Shrier LA. Diagnostic tests for chlamydial and gonorrheal infections. Semin Pediatr Infect Dis 2005; 16: 192-8. Brocklehurst P, Rooney G. Interventions for treating genital chlamydia trachomatis infection in pregnancy. Cochrane Database Syst Rev 1998; 4 ; : 000054. 5. Adair CD, Gunter M, Stovall TG, McElroy G, Veille JC, Ernest JM. Chlamydia in pregnancy: a randomized trial of azithromycin and erythromycin. obstet Gynecol 1998; 91: 165-8. Brocklehurst P. Antibiotics for gonorrhoea in pregnancy. Cochrane Database Syst Rev 2002; 2 ; : CD000098. 7. Cook RL, Hutchison SL, ostergaard L, Braithwaite RS, Ness RB. Systematic review: noninvasive testing for Chlamydia trachomatis and Neisseria gonorrhea. Ann Intern Med 2005; 142: 914-25. Ramus RM, Sheffield JS, Mayfield JA, Wendel GD Jr. A randomized trial that compared oral cefixime and intramuscular ceftriaxone for the treatment of gonorrhea in pregnancy. J obstet Gynecol 2001; 185: 629-32. Chen KT, Segu M, Lumey LH, Kuhn L, Carter RJ, Bulterys M, et al., for the New York City Perinatal AIDS Collaborative Transmission Study PACTS ; Group. Genital herpes simplex virus infection and perinatal transmission of human immunodeficiency virus. obstet Gynecol 2005; 106: 1341-8. Sheffeld JS, Hollier LM, Hill JB, Stuart GS, Wendel GD. Acyclovir prophylaxis to prevent herpes simplex virus recurrence at delivery: a systematic review. obstet Gynecol 2003; 102: 1396-403. Watts DH, Brown ZA, Money D, Selke S, Huang ML, Sacks SL, et al. A double-blind, randomized, placebocontrolled trial of acyclovir in late pregnancy for the reduction of herpes simplex virus shedding and cesarean delivery. J obstet Gynecol 2003; 188: 836-43 and indocin.
| Discount ErythromycinCanada is now facing an oxy epidemic site site just some of the victims of the oxy epidemic click here to see their stories on the memorial page i writing this to let people know how dangerous this drug is when misused, for instance, ergthromycin solution.
You may not be able to take erythromycin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above and isordil.
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Routinely performs the D test on any MRSA cultures isolated from patients less than 18 years of age that demonstrate e4ythromycin resistance with clindamycin susceptibility during initial testing. The results of the D test are reported in the microbiology section of laboratory results, but usually takes slightly longer than the initial susceptibility report to be available. The emergence of CA-MRSA has led to a resurgence of interest in therapy options for S. aureus infections. MRSA isolates circulating in the community have antibiotic susceptibility profiles that differ from that of nosocomial MRSA infections. Clindamycin represents a useful option for therapy for various CA-MRSA infections that are D test-negative, including musculoskeletal infections and skin and soft-tissue infections. In addition to the potential use of clindamycin for CA-MRSA infections, trimethoprim-sulfamethoxazole TMPSMX, Bactrim, Septra ; may also be an option for empiric therapy for mild to moderate infections. Based on the MRSA isolates identified at our institution, there is a 99% susceptibility rate to TMP-SMX. Although few adequately randomized controlled trials have documented the efficacy of TMP-SMX against MRSA infections, a large body and
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Table. 2. Clinicopathologic features of patients with PaCa.
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An early report describing the application of liquid chromatography for the analysis of EA, EB and leucomycins was published in 1973 [24]. Erhthromycin has a low molar absorptivity as it lacks a suitable chromophore. Thus, specific, selective and sensitive UV detection of this compound is difficult. To overcome this problem low UV wavelengths, where substantial UV absorption occurs, have been used. This generally necessitates the use of extensive precolumn extraction procedures in order to eliminate potentially interfering components, particularly when using complex matrices such as biological fluids and tissues. Generally, a wavelength of 215 nm has proved to be the most useful wavelength to monitor erythromycin and related compounds and has been extensively used in most applications and
levocetirizine and
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The pharmacokinetics and safety of single ascending doses of clarithromycin 6-0-methylerythromycin A ; were assessed in a placebo-controlled, double-blind, randomized trial with 39 healthy male volunteers. Subjects were randomized to receive single doses of either placebo or 100, 200, 400, or 1, 200 mg of clarithromycin. Blood and urine collections were performed over the 24 h following administration of the test preparation. Biological specimens were analyzed for clarithromycin and 14 R ; -hydroxyclarithromycin content by a high-performance liquid chromatographic technique. The pharmacokinetics of clarithromycin appeared to be dose dependent, with terminal disposition half-life ranging from 2.3 to 6.0 h and mean standard deviation area under the concentration-versus-time curve from time 0 to infinity for plasma ranging from 1.67 : 0.48 to 3.72 t 1.26 mgtliter. h per 100-mg dose over the 100- to 1, 200-mg dose range. Similar dose dependency was noted in the pharmacokinetics of the 14 R ; -hydroxy metabolite. Mean urinary excretion of clarithromycin and its 14 R ; -hydroxy metabolite ranged from 11.5 to 17.5% and 5.3 to 8.81% of the administered dose, respectivety. Urinary excretion data and plasma metabolite parent compound concentration ratio data suggested that capacity-limited formation of the active metabolite may account, at least in part, for the nonlinear pharmacokinetics of darithromycin. No substantive dose-related trend was observed for the renal clearance of either compound. There were no clinically significant drug-related alterations in laboratory and nonlaboratory safety parameters. In addition, there was no significant difference between placebo and clarithromycin recipients in the incidence or severity of adverse events. Clarithromycin appears to be safe and well tolerated.
The microbiologist will give further advice when telephoning the positive result. 11.12 Wound Infections traumatic surgical ; Staph. aureus Flucloxicillin if allergic to Pen. Erythromyin 500mg QDS PO and lopid.
P.P.H.U. `BIOFARM' Sp. z o.o. 31 12 08 Norgine Pharma 31 12 08.
Tillie-Leblond I et al. Annals of Internal Medicine 2006; 144: 390-6.
Adult dose 1 spray 5 mg ; in each nostril, can be repeated after 15 min if no relief; not to exceed 0 mg d pediatric dose 1 spray in 1 nostril is adequate for child, which will deliver 5 mg contraindications documented hypersensitivity; heart disease; uncontrolled hypertension; has used sumatriptan or zolmitriptan within previous 24 h; within 2 wk of discontinuing maois interactions increases effects of heparin and toxicity of nitroglycerin, propranolol, erythromycin, and clarithromycin pregnancy c - safety for use during pregnancy has not been established.
Magistrate incorrectly concluded the SERS' examiner, Dr. Wolfe, satisfied the requirement of R.C. 3309.39 C ; that the SERS' examining physician be "disinterested." Additionally, relator contends the magistrate erred in concluding there was no patent inconsistency among Dr. Wolfe's clinical finding, disability opinion and the objective test results. Instead, the magistrate characterized the issue as a medical disagreement, for instance, erythromycin eye ointment.
Clarithromycin is classified as an FDA Pregnancy Category C drug. TMP SMZ may be used as an alternate agent in patients who are allergic to or cannot tolerate macrolides. 6 TMP SMZ is classified as an FDA Pregnancy Category C drug. It should not be given to pregnant women, nursing mothers, premature neonates, or infants 2 months of age. 7 Treatment of pertussis is not an FDA approved use of azithromycin, but CDC has recommended it as first line treatment. Data on use of azithromycin in infants, 6months of age is limited, but CDC recommends it as preferred drug for pertussis in infants under 1 month of age. In infants 1-5 months, erythromycin and azithromycin were equally recommended. 8 Whenever available the estolate preparation of erythromycin should be used and exelon.
I would like to thank the Ministry of Health in UAE who allowed me to conduct the project in primary care Abu Dhabi. I wish to thank the GPs who participated in the study and gave freely of their time. With special thanks to those who contacted me for discussion of the subject and offered their help for any encountered problems. Special thanks to my local mentor Professor Greg Papworth who encouraged me to do the Masters degree and our continuous discussion enlightened me on the chosen topic. Lastly, I thank my family who tolerated my frustration during my study and had faith that I can succeed in achieving my goals.
Sertraline, Cont. ; 2 Doxepin, 1276 4 Erythromycin, 1057 2 Ethotoin, 681 1 Fenfluramine, 1142 2 Fosphenytoin, 681 2 Hydantoins, 681 2 Imipramine, 1276 4 L-Tryptophan, 1061 4 Macrolide Antibiotics, 1057 1 MAO Inhibitors, 1058 1 Mazindol, 1142 2 Mephenytoin, 681 1 Methamphetamine, 1142 4 Metoprolol, 246 Nefazodone, 870 2 Nortriptyline, 1276 1 Phendimetrazine, 1142 1 Phenelzine, 1058 1 Phenmetrazine, 1142 1 Phentermine, 1142 1 Phenylpropanolamine, 1142 2 Phenytoin, 681 4 Propranolol, 246 2 Protriptyline, 1276 1 Selegiline, 1058 1 Sibutramine, 1068 4 St. John's Wort, 1059 1 Sumatriptan, 1131 1 Sympathomimetics, 1142 1 Tranylcypromine, 1058 4 Trazodone, 1060 2 Tricyclic Antidepressants, 1276 2 Trimipramine, 1276 4 Troleandomycin, 1057 4 Warfarin, 128 3 Zolpidem, 1326 Serzone, see Nefazodone Sevoflurane, 2 Labetalol, 730 Siberian Ginseng, 4 Digoxin, 484 Sibutramine, 1 Dextromethorphan, 1062 1 Dihydroergotamine, 1063 1 Ergot Alkaloids, 1063 1 Ergotamine, 1063 1 Fluoxetine, 1068 1 Fluvoxamine, 1068 1 Isocarboxazid, 1065 1 Lithium, 1064 1 MAO Inhibitors, 1065 1 Meperidine, 1066 1 Methysergide, 1063 1 Naratriptan, 1067 1 Nefazodone, 1068 1 Paroxetine, 1068 1 Phenelzine, 1065 1 Rizatriptan, 1067 1 Selective 5-HT1 Receptor Agonists, 1067 1 Serotonin Reuptake Inhibitors, 1068 1 Sertraline, 1068 1 Sumatriptan, 1067 1 Tranylcypromine, 1065 1 Tryptophan, 1069 1 Venlafaxine, 1068 1 Zolmitriptan, 1067 Sildenafil, 1 Amprenavir, 1070 1 Amyl Nitrate, 887 1 Indinavir, 1070 1 Isosorbide Dinitrate, 887 1 Isosorbide Mononitrate, 887 1 Nelfinavir, 1070 Sildenafil, Cont. ; 1 Nitrates, 887 1 Nitroglycerin, 887 1 Protease Inhibitors, 1070 1 Ritonavir, 1070 1 Saquinavir, 1070 Simron, see Ferrous Gluconate Simvastatin, 2 Anticoagulants, 103 4 Azithromycin, 637 2 Azole Antifungal Agents, 630 2 Bile Acid Sequestrants, 631 2 Cholestyramine, 631 4 Clarithromycin, 637 2 Colestipol, 631 2 Diltiazem, 632 4 Erythromycin, 637 4 Fibers, 633 2 Food, 634 1 Gemfibrozil, 635 2 Grapefruit Juice, 634 2 Itraconazole, 630 4 Macrolide Antibiotics, 637 4 Nefazodone, 638 4 Oat Bran, 633 4 Pectin, 633 2 Verapamil, 639 2 Warfarin, 103 Sinemet, see Carbidopa Sinequan, see Doxepin Sinex, see Phenylephrine Sirolimus, Diltiazem, 1154 Metronidazole, 1157 Slo-bid, see Theophylline Slo-phyllin, see Theophylline Slow FE, see Ferrous Sulfate Slow-K, see Potassium Chloride SMZ-TMP, see Trimethoprim Sulfamethoxazole Sodium Acetate, 2 Amphetamine, 58 2 Anorexiants, 58 3 Aspirin, 1049 2 Chlorpropamide, 1129 3 Choline Salicylate, 1049 2 Demeclocycline, 1174 2 Dextroamphetamine, 58 Diflunisal, 1049 2 Doxycycline, 1174 2 Ephedrine, 1145 5 Flecainide, 583 2 Lithium, 780 3 Magnesium Salicylate, 1049 4 Mecamylamine, 810 2 Methacycline, 1174 2 Methamphetamine, 58 5 Methenamine, 832 5 Methotrexate, 846 2 Minocycline, 1174 2 Oxytetracycline, 1174 2 Pseudoephedrine, 1145 4 Quinidine, 1016 3 Salicylates, 1049 3 Salsalate, 1049 3 Sodium Salicylate, 1049 3 Sodium Thiosalicylate, 1049 2 Sulfonylureas, 1129 2 Sympathomimetics, 1145 2 Tetracycline, 1174 2 Tetracyclines, 1174 Sodium Acid Phosphate, 3 Amphetamine, 57 3 Anorexiants, 57 3 Chlorpropamide, 1128.
When the drugs were first marketed, their side-effects were claimed to be minimal, but experience over the years has shown them to be potentially very hazardous.
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