Brune ME, Buckner SA, Polakowski J, Kerwin JF, and Hancock AA 1995 ; Pharmacological antagonism of 1-adrenergic agonist induced increases in canine intra-urethral pressure in vivo. Drug Dev Res 34: 267275. Brune ME, Katwala SP, Milicic IP, Buckner SA, Ireland LM, Kerwin JF Jr, and Hancock AA 1996 ; Effects of selective and nonselective 1-adrenoceptor antagonists on intraurethral and arterial pressures in intact conscious dogs. Pharmacology 53: 356 368. Bylund DB, Eikenberg DC, Hieble JP, Langer SZ, Lefkowitz RJ, Minneman KP.
104 Current Drug Discovery Technologies, 2004, Vol. 1, No. 1, because clavulanate and alcohol.
BACTEROIDES SPP. AND OTHER GRAM-NEGATIVE ANAEROBES Chromosomal class A -lactamases with predominantly cephalosporinase activity are virtually ubiquitous in Bacteroides fragilis group isolates 215, 266 ; , although their amount varies greatly among isolates. Like most class A enzymes, they are inhibited by clavulanate, tazobactam, and sulbactam 8 ; . These enzymes determine the natural resistance of B. fragilis isolates to many penicillins and cephalosporins, and their importance is underscored by the fact that most B. fragilis group isolates are more susceptible to piperacillin-tazobactam, ticarcillin-clavulanate, amoxicillin-clavulanate, and ampicillin-sulbactam than to piperacillin, ticarcillin, amoxicillin, or ampicillin 7, 8 ; . Moreover, Maskell et al. 149 ; found that clavulanate, 2 g ml, reduced the MICs of cephaloridine, cefotaxime, and ceftriaxone by 16-fold or more for most B. fragilis, B. ovatus, B. thetaiotaomicron, and B. vulgatus isolates and also reduced the MICs of cefsulodin, cefoperazone, and ceftazidime for B. fragilis species. On the other hand, clavulanate caused only twoto fourfold reductions in the MICs of cefsulodin, cefoperazone, and ceftazidime for resistant isolates of B. ovatus, B. thetaiotaomicron, and B. vulgatus, and it appears that factors other than -lactamase contributed to resistance in these species. The extended-spectrum cephalosporins cefotaxime, and ceftizoxime appear active at 16 g against some B. fragilis strains, probably those with the smallest amount of chromosomal enzyme. Nevertheless, it seems prudent to avoid these agents in therapy and to use -lactamaseinhibitor combina.
Colonizer in patients who have received broad spectrum antibiotics especially carbapenems ; . It is important to differentiate colonization from infection. Opportunistic pathogen respiratory tract, bacteremia, urinary and wound infections ; in predisposed malignancy, ICU, previous antibiotics, immunosuppression ; patients. Multiple resistance to cephalosporins, quinolones, and aminoglycosides. In serious infections, combination therapy according to susceptibility report ; is recommended. NB: Very high incidence of ticarcillin-clavulanate resistance locally. Recovered from urogenital tract of women. Pathogenic role not established. Resistant to aminoglycosides.
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Amiodarone hcl .T-32 AMITIZA.T-33 amitrip hcl chlordiazepoxide .T-49 amitriptyline hcl .T-49 amitriptyline hcl perphenazine .T-49 AMMONIUM CHLORIDE.T-1 ammonium lactate.T-37 AMMONIUM LACTATE.T-47 amox tr potassium clavulanate .T-8 amoxapine .T-49 amoxicillin trihydrate.T-8 Amoxil .T-8 amphet asp amphet d-amphet .T-5 Amphocin.T-14 AMPHOTEC.T-14 amphotericin b .T-14 ampicillin sodium sulbactam na .T-8 ampicillin trihydrate .T-8 amylase lipase protease.T-35 Anafranil .T-49 anagrelide hcl .T-43 Anaprox.T-3 Ancef.T-6 ANCOBON.T-14 ANDRODERM.T-5 ANDROGEL.T-5 Anexsia .T-3 Ansaid .T-2 ANTABUSE .T-43 anthralin.T-42 Antilirium.T-47 antipyrine benzocaine glycerin.T-42 Antivert .T-13 ANTIVERT.T-13 ANTIZOL .T-43 Apresazide.T-41 Apresoline .T-41 APTIVUS.T-26 AQUACHLORAL .T-28 ARALAST .T-37 Aralen Phosphate .T-24 ARANESP .T-40 Arava.T-44 Aredia.T-44 ARESTIN.T-35 ARICEPT.T-47 and
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Trauma management and definitive wound care: Wound pathogens Cougars large cats - Pasteurella, Pseudomonas Bears- similar to dog flora- Micrococcus, Streptococcus Ungulates - Pasteurella, Acinetobacillus Crocodiles alligators - Aeromonas Trauma management and definitive wound care: Antibiotic prophlaxis Choose broad spectrum coverage Cover animal-specific pathogens Good choices for most Best: Amoxacillin-clavulanate Cephalosporins cefuroxime cephalexin ; + metronidazole Clindamycin + trovafloxacin ?risk ; , doxycycline, gatifloxacin, moxifloxacin Experimental: ketolides, GAR-936 semisynthetic glycylcycline, Daptomycin? cyclic lipopeptide ; Mechanism of and prevention of attacks: Black bears Black bear Ursus americanus ; Generally smaller than other North American bears Most numerous widely distributed Attacks Usually easily frightened away by aggression Sows with cubs not aggressive Mechanism of and prevention of attacks: Brown bears Brown bear Ursus arctos ; Grizzly Ursus arctos horribilis ; Kodiak Ursus middendorfi ; Attacks Predation rare; attempt to minimize perceived threat Avoid human interaction NOT easily frightened away by aggression Sows with cubs VERY aggressive - account for 80% of attacks Mechanism of and prevention of attacks : Brown bears Brown bear attacks Face head often first attacked Bite chew Claw Batting Falls from trees Consumption more common in habituated bears Mechanism of and prevention of attacks: Brown bears Prevention: Avoid habituation Avoid encounters Travel in groups of 4 or more Make noise-avoid surprising a bear Extra vigilance when hiking upwind Remain alert tracks, carcasses, scat ; Mechanism of and prevention of attacks: Brown bears Minimizing injury in an encounter Predatory- FIGHT pray ; Provoked sudden encounter Remove the threat! Avoid eye contact Identify yourself as human Back away DON'T RUN ; Play dead AND STAY DEAD! Bear spray?.
Tabs per month, but have taken as much as three day in the past but found just built a tolerance to the effect, stopped working ; , and have never had a problem and
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`Before leaving for Malta, we had received informative material from the new Maltese medicines agency, which has responsibility for human medicinal products only, as well as material from a directorate under the Ministry of Rural Affairs and the Environment, which handles veterinary medicinal products. The purpose of our visit was to prepare the Maltese inspectors for a subsequent visit by the Canadian medicines authority. It could also be considered a trust-building exercise and an opportunity for colleagues to exchange viewpoints. Before our visit, the Maltese Medicines Authority MMA ; had completed a two-year `twinning programme' with a UK and an Irish inspector who had assisted with the implementation of new legislation and a quality management system. The programme ended the day before our arrival, and its completion was celebrated in style. The chief executive officer of the MMA gave me and my Spanish colleague an informative introduction to the organisation. The MMA houses a pre-licensing and a post-licensing directorate as well as an inspections and enforcement directorate, and employs a staff of 40. We reviewed recent legislation to ensure that the authority was empowered to issue or withdraw authorisations for handling medicines and that inspectors had access to the companies. We also reviewed the instructions for performing inspections.
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Tests were NOT developed for these species and should NOT be used for them. False positive results with Acinetobacter are common owing to inherent susceptibility to clavulanate, whilst S. maltophilia may give positive results via inhibition of its chromosomal L -lactamase. -2 ESBLs may occur in these genera e.g. VEB-1 in and arava.
ALPHAGAN P. 41 ALREX . 41 ALTACE. 26 ALTOPREV . 26 amantadine . 17, 19 AMBIEN . 46 AMICAR 1000 mg . 23 amiloride. 25 amiloride hydrochlorothiazide . 25 aminocaproic acid. 23 aminophylline . 45 aminophylline inj. 45 amiodarone . 23 amiodarone inj. 23 amitriptyline . 10 ammonium lactate 12% . 31 amnesteem . 30 AMOXAPINE. 10 amoxicillin. 6 amoxicillin clavulanate . 6 AMOXIL PEDIATRIC DROPS. 6 ampicillin . 6 ampicillin inj . 6 anagrelide . 23 ANALPRAM-HC . 30 ANCOBON . 11 ANDRODERM . 36 ANDROGEL . 36 ANTABUSE . 31 anthralin . 31 ANTHRAX VACCINE ADSORBED . 39 ANTIVERT 50 mg. 11 APOKYN . 17 APTIVUS . 19 ARALEN inj . 16 ARANESP . 22 ARICEPT . 9 ARIMIDEX . 38 AROMASIN . 38 ASACOL . 40 ASTELIN . 43 ATACAND . 26 ATACAND HCT . 25, 26 ATARAX 100 mg. 43 atenolol . 20, 24 49.
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| Clavulanate pregnancyBacterial rhinosinusitis and AOM caused by H influenzae as well as 50% to 75% of the children infected with M catarrhalis also will recover spontaneously.45 Furthermore, only S pneumoniae that are highly resistant to penicillin will not respond to conventional doses of amoxicillin. Therefore, approximately 80% of children with acute bacterial rhinosinusitis and AOM will respond to treatment with amoxicillin. However, risk factors for the presence of penicillin-resistant isolates in children include daycare attendance, recent antimicrobial treatment 90 days ; , and age younger than 2 years.46 Antimicrobial pharmacokinetics are important considerations for use against a pathogen. It is important to evaluate the in vitro activity of an antimicrobial against the pathogen in conjunction with achievable concentrations at the site of infection. For example, macrolides such as clarithromycin and azithromycin are concentrated in leukocytes and have higher concentrations in alveolar epithelial lining fluid tissues compared with plasma.47 Therefore, these agents are very active for pneumonia. In addition, -lactams and some macrolides work in a time-dependent manner, which means that the duration of time their concentration stays above the minimum inhibitory concentration at the site of infection is critical to their success. Based on these criteria, high-dose amoxicillin remains a potent agent against S pneumoniae. Other highly active -lactams effective against S pneumoniae include cefdinir, cefpodoxime, cefprozil, and cefuroxime.48 Ceftriaxone also is highly effective against S pneumoniae. Due to high rates of -lactamase production by H influenzae and M catarrhalis, clavulanate -lactamase inhibitor ; is required in addition if amoxicillin is used. However, 3 cephalosporins cefixime, ceftibuten, and ceftriaxone ; have been shown to be highly effective against these pathogens.48 An important practical consideration for administration of antimicrobials is patient compliance. This is specifically important in children since it may be difficult to ensure administration of antimicrobials if dosing is too frequent or if they are not palatable. Table 1 lists the palatability ratings for common antimicrobial suspensions used for ARIs. When overall taste ratings were adjusted for duration and dosing of the antimicrobial, cefdinir was the most palatable oral suspension among potent antipneumococcal -lactams.49 These data may be useful for making decisions about use of antimicrobials, particularly in children. It should be noted that ciprofloxacin should be avoided in children due to concerns about cartilage toxicity.
From: George E. Reynolds, Brig. Gen., USAF, MC, Director of Professional Services, Office of the Surgeon General. To: Wilford Hall USAF Medical Center SG, Lackland AFB, TX. Subject: Clinical Investigation Proposal #517: Bone Scanning as a Screening Test in Breast Cancer. Document Type: Memorandum. Date: 14 January 1974 and atorvastatin.
In comparative studies, fleroxacin and ofloxacin have been found to be as effective as amoxicillin-clavulanate and first- and second-generation oral cephalosporins in the treatment of uncomplicated mild to moderate skin infection.
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A draft copy of this completed form was left with Bonnie Sheridan, RN Housing Director at an exit conference on October 22, 2004. Any correction orders issued as a result of the on-site visit and the final Licensing Survey Form will arrive by certified mail to the licensee within 3 weeks of this exit conference see Correction Order form HE-01239-03 ; . If you have any questions about the Licensing Survey Form or the survey results, please contact the Minnesota Department of Health, 651 ; 215-8703. After supervisory review, this form will be posted on the MDH website. General information about ALHCP is also available on the website: : health ate.mn divs fpc profinfo cms alhcp alhcpsurvey Regulations can be viewed on the Internet: : revisor.leg ate.mn stats for MN statutes ; : revisor.leg ate.mn arule for MN Rules ; . Form Revision 7 04 and
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Others are combination drugs - amoxicillin and clavulanate, for instance.
H. influenzae n 520 ; Antibacterial Ampicillin All isolates -lactamase -lactamase + Amoxycillin All isolates -lactamase -lactamase + Amoxycillin clavulahate All isolates -lactamase -lactamase + Cefaclor All isolates -lactamase -lactamase + Cefdinir All isolates -lactamase -lactamase + Cefixime All isolates -lactamase -lactamase + Cefpodoxime All isolates -lactamase -lactamase + Cefprozil All isolates -lactamase -lactamase + Cefuroxime All isolates -lactamase -lactamase + INT % ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 7 1.3 ; 6 1.4 ; 1 1.1 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 22 4.2 ; 6 1.4 ; 16 18.2 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 12 2.3 ; 3 0.7 ; 9 10.2 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; RES % ; 88 16.9 ; 0 0.0 ; 88 100 ; 90 17.3 ; 3 0.7 ; 87 98.9 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 2 0.4 ; 0 0.0 ; 2 2.3 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 4 0.8 ; 0 0.0 ; 4 4.5 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; MIC90 mg L ; 16 0.5 16 MIC range mg L ; 0.12-32 0.12-1 4-32 INT * % ; 11 7.9 ; 0 0.0 ; 116 84.1 ; 7 5.0 ; 0 0.0 ; 7 5.1 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 5 3.6 ; 0 0.0 ; 5 3.6 ; 0 0.0 ; 0 0.0 ; 5 3.6 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 6 4.3 ; 0 0.0 ; 6 4.3 ; 1 0.7 ; 0 0.0 ; 1 0.7 ; M. catarrhalis n 140 ; RES * % ; 116 82.9 ; 0 0.0 ; 116 84.1 ; 122 87.1 ; 0 0.0 ; 122 88.4 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; 1 0.7 ; 0 0.0 ; 1 0.7 ; 0 0.0 ; 0 0.0 ; 0 0.0 ; MIC90 mg L ; 16 -a 16 -a 0.25 -a 0.25 8 -a 8 0.25 -a 0.25 0.5 -a 0.5 1 -a 1 8 -a MIC range mg L ; 0.12-32 0.12 0.12-32 and
azelaic.
Is there a government regulated dispensing fee? Yes No there is no dispensing fee If yes, please describe fee and how applied: Does the government set Maximum Selling Prices for medicines? Yes No If any of the survey medicines have Maximum Prices, list them.
Should be considered. The initial treatment must be considered when choosing an alternative regimen. If a patient failed high-dose amoxicillin initially, neither trimethoprim-sulfamethoxazole nor erythromycin-sulfisoxazole should be selected because of the high cross-resistance that is observed with penicillin-nonsusceptible S. pneumoniae strains against sulfa drugs see Table 1-2 ; . In addition, if high-dose amoxicillin was used with no clinical improvement, amoxicillin-clavulanate will provide no additional benefit for pneumococci. In S. pneumoniae, resistance to -lactam drugs occurs through alterations in the PBPs and not through the production of -lactamases. If amoxicillinclavulanate was used initially with no response, an oral second-generation cephalosporin or intramuscular ceftriaxone is advocated for use. Fluoroquinolones are not recommended to treat otitis media because of its associated risk of impaired bone and joint development in children. Although human data do not appear to support the concern for quinolone-induced arthropathy, quinolone use in children should be reserved for life-threatening situations when other drugs are not possible options. Sinusitis Guidelines published in 2004 by the American Academy of Otolaryngology Head and Neck Surgery, the American Academy of Otolaryngic Allergy, and the American Rhinologic Society include high-dose amoxicillin or highdose amoxicillin-clavulanate as first-line therapy for sinusitis in children and adults. Treatment guidelines are summarized in Table 1-4 and provide therapy recommendations for adults and children. Streptococcus pneumoniae is the cause of bacterial sinusitis in about 33% of all cases. With sinusitis, cultures often are not obtained and drug therapy is approached empirically. Because serious complications can be associated with pneumococcal sinus infections, empiric therapy must always include coverage for S. pneumoniae. Treatment guidelines for adults and children categorize sinus infections into two groups: those with mild disease and no previous antibiotic drugs in the preceding 46 weeks, and individuals with mild disease having previous antibiotic drug exposure or those with moderate disease. Recent antibiotic drug exposure is a risk for infections caused by resistant pathogens, most commonly resistant S. pneumoniae. Antibiotic drugs Pharmacotherapy Self-Assessment Program, 5th Edition and
azithromycin.
But, for whatever reason, the manufacturer decided to make the canadian drugs a different color.
Placebo response in dysthymia. In this study, 10 day placebo responders who continued to receiving placebo tablets were compared to patients who had their medication discontinued. Half of the patients in each condition relapsed within 6 weeks proving that and
azulfidine and
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Researchers without explicit mention, whereas in Psychology the readers may come from a broader background, and the writer has to be more explicit. Discursive practices in Psychology may demand more direct forms of writing when criticising ones peers, in order for the writers claims to be made more convincing. The fact that in Psychology the percentage of critical speech acts in the Introduction section of the RAs is higher than in the same section in Chemistry could possibly be explained in terms of the dependence in Psychology on textual devices for gap creation: in Chemistry, the results are the most powerful support of their knowledge claims, consequently writers prefer to dedicate valuable space hard science journals sometimes charge writers by the page for their contribution ; to this section instead of the introduction. Another factor, as Bazerman 1988 ; has pointed out, is that the assumed background knowledge in hard science fields allows the writer to avoid having to use an extensive system of references to previous work, thus writers may not have to point out any particular conflict to establish their research space in the introduction.
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Amoxicillin and cpavulanate potassium should be taken with a meal or snack to reduce stomach upset and
bactrim.
Dr. TIBOR RUDISCH assistant professor Prof. habil. GBOR BLINT professor Pharmacodynamics Department Prof. habil. GYRGY FALKAY professor, Head of Department Department of Drug Regulatory Prof. TAMS PAL Professor, Head Affairs of Department Department of Medical Genetics Prof. JNOS SZAB, professor, Head of Department.
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Taking certain drugs when on ARV treatment can be very dangerous. These drugs can increase the concentration of ARV drugs in the blood and make them toxic. The concentration of these drugs in the blood can also increase when mixed with ARVs and they become toxic. Certain drugs can decrease the concentration of ARV drugs in the blood and make them ineffective. Never take drugs without consulting a doctor first no self-medication when taking ARV drugs.
Keflex Cap, Susp $ Macrodantin Cap $ Vibramycin Cap $ Cap, Tab, Susp $ E-Mycin, Eryc, Pediazole clarithromycin * Biaxin Tab $$ * Must have documented H.Pylori infection. * Limited to 500mg twice dialy for 7 days. tetracycline * Achromycin V Cap $ sulfamethoxazole trimethoprim * Bactrim, Septra Susp, Tab $ amoxicillin clavulanate * Augmentin Chew, Susp $$$$ For suspension: 200mg 5ml and 400mg 5ml strengths are covered. disopyramide * Norpace Cap $ procainamide * Pronestyl Cap $ warfarin * Coumadin Tab $$ phenytoin * Dilantin Cap $ lisinopril * Prinvil, Zestril Tab $ lisinopril hctz * Zestoretic Tab $ captopril * Capoten Tab $ irbesartan Avapro Tab $$$ valsartan Diovan Tab $$$ valsartan hydrochlorothiazide Diovan HCT Tab $$$ amitriptyline * Elavil Tab $ trazodone * Desyrel Tab.
328. The PADHOC Device is a Better Guide to the Actual Incapacity Suffered by Claudicants than the Gold Standard Constant Load Treadmill Test - Coughlin P.A., Kent P.J., Berridge D.C. et al. [P.A. Coughlin, Department of Vascular and Endovascular Surgery, St. James's University Hospital, Leeds, United Kingdom] - EUR. J. VASC. ENDOVASC. SURG. 2006 32 6 ; - summ in ENGL Background: The Constant Load Treadmill Test CLTT ; is currently the primary method used to measure walking impairment in patients with peripheral vascular disease. The aim of this study was to compare the CLTT and PADHOC device as assessments of walking impairment. Methods: 55 patients with intermittent claudication underwent a CLTT and a Double Physiological Walking Test DPWT ; using the PADHOC device. Health-related quality of life was measured using the Short Form 36 and the Claudication Scale. Results: The initial claudication and maximum walking distance from the first part of the DPWT showed the best correlation with domains of pain and physical function. Conclusions: The DPWT is more representative of the functional incapacity experienced by patients with intermittent claudication. We believe that the PADHOC is a suitable alternative to the CLTT in the assessment of this patient group. 2006 Elsevier Ltd. All rights reserved. 329. A comparison of physical functional performance and strength in women with fibromyalgia, age- and weight-matched controls, and older women who are healthy - Panton L.B., Kingsley J.D., Toole T. et al. [Dr. L.B. Panton, Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL 32306, United States] PHYS. THER. 2006 86 11 ; - summ in ENGL Background and Purpose. The purpose of this study was to compare functionality and strength among women with fibromyalgia FM ; , women without FM, and older women. Subjects. Twenty nine women with FM age [X SD] 46 7 years ; , 12 age- and weight-matched women without FM age 44 8 years ; , and 38 older women who were healthy age 71 7 years ; participated. Methods. The Continuous Scale-Physical Functional Performance Test CS-PFP ; was used to assess functionality. Isokinetic leg strength was measured at 60 s, and handgrip strength was measured using a handgrip dynamometer. Results. The women without FM had significantly higher functionality scores compared with women with FM and older women. There were no differences in functionality between women with FM and older women. Strength measures for the leg were higher in women without FM compared with women with FM and older women, and both women with and without FM had higher grip strengths compared with older women. Discussion and Conclusion. This study demonstrated that women with FM and older women who are healthy have similar lowerbody strength and functionality, potentially enhancing the risk for premature age-associated disability. Section 19 vol 50.2, for example, amoxicillin clavulanate potassium.
and
ampicillin.
DRUG ZANTIN Cephalosporins, 4th Generation Beta-lactam, Penicillins Amino Derivative Penicillins DRUG amoxicillin amoxicillin clavulanate AMOXIL ampicillin AUGMENTIN BICILLIN LA, BICILLIN D125CR penicillin penicillin G penicillin IV PRINCIPEN UNASYN Extended Spectrum Penicillins DRUG GEOCILLIN PIPRACIL piperacillin TIMENTIN Penicillinase-resistant Penicillins DRUG dicloxacillin nafcillin nafcillin with dextrose IV Beta-lactam, Other Carbapenem DRUG MERREM Glycylclyclines DRUG TYGACIL Macrolides Erythromycins DRUG ERYC, ERY-TAB, ERYPED, ERYTHROCIN, E.E.S erythrocin lactobionate erythromycin 400mg erythromycin and sulfisoxazole.